Alexander Lorenz

2024

Measuring Meiotic Recombination Frequency in Schizosaccharomyces pombe Using an Engineered Genetic Interval

Lorenz, A., 12 Nov 2024, Schizosaccharomyces pombe: : Methods and Protocols. New York, NY: Humana Press, Vol. 2862. p. 277-295 19 p. (Methods in Molecular Biology; vol. 2862).

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

Candida auris undergoes adhesin-dependent and -independent cellular aggregation

Pelletier, C., Shaw, S., Alsayegh, S. M. A. E. H. M. A., Brown, A. J. P. & Lorenz, A. (Corresponding Author), 11 Mar 2024, In: PLoS Pathogens. 20, 3, 36 p., e1012076.

Research output: Contribution to journal › Article › peer-review

Open Access

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12 Citations (Scopus)

21 Downloads (Pure)

2022

Mendel's laws of heredity on his 200th birthday: What have we learned by considering exceptions?

Wolf, J. B. (Corresponding Author), Ferguson-Smith, A. C. & Lorenz, A., 1 Jul 2022, In: Heredity. 129, 1, p. 1-3 3 p.

Research output: Contribution to journal › Editorial › peer-review

Open Access

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9 Citations (Scopus)

11 Downloads (Pure)

Gene conversion: a non-Mendelian process integral to meiotic recombination

Lorenz, A. (Corresponding Author) & Mpaulo, S. J., Jul 2022, In: Heredity. 129, p. 56-63 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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16 Citations (Scopus)

24 Downloads (Pure)

Genetic Transformation of Candida auris via Homology-Directed Repair Using a Standard Lithium Acetate Protocol

Bravo Ruiz, G. & Lorenz, A. (Corresponding Author), 10 Jun 2022, Candida auris: Methods and Protocols. Lorenz, A. (ed.). 1 ed. New York: Springer , p. 95-110 16 p. (Methods in Molecular Biology; vol. 2517).

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

3 Citations (Scopus)

Labelling of Candida auris Cell Walls to Examine Levels of PAMP Exposure by Flow Cytometry and Fluorescence Microscopy

Pelletier, C. & Lorenz, A. (Corresponding Author), 10 Jun 2022, Candida auris: Methods and Protocols. Lorenz, A. (ed.). 1 ed. Totawa New Jersey: Springer , p. 179-187 9 p. (Methods in Molecular Biology; vol. 2517).

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

1 Citation (Scopus)

Preface: Candida auris: Methods in Molecular Biology

Lorenz, A. (Corresponding Author), 10 Jun 2022, Candida auris: Methods and Protocols. Lorenz, A. (ed.). 1 ed. New York: Humana Press, Vol. 2517. p. v 1 p. (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceeding › Foreword/postscript

New tools for the new bug Candida auris

Lorenz, A. (Corresponding Author) & Papon, N., 1 Mar 2022, In: Trends in Microbiology. 30, 3, p. 203-205 3 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

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3 Citations (Scopus)

8 Downloads (Pure)

2021

The curious case of nonrepetitive centromeric DNA sequences in Candida auris and related species

Lorenz, A. (Corresponding Author) & Papon, N., 31 Aug 2021, In: mBio. 12, 4, 5 p., e01476-21.

Research output: Contribution to journal › Literature review › peer-review

Open Access

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2 Citations (Scopus)

12 Downloads (Pure)

What do we know about the biology of the emerging fungal pathogen of humans Candida auris?  

Bravo Ruiz, G. & Lorenz, A., Jan 2021, In: Microbiological Research. 242, 13 p., 126621.

Research output: Contribution to journal › Article › peer-review

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51 Citations (Scopus)

9 Downloads (Pure)

2020

Is Candida auris sexual?

Lorenz, A. (Corresponding Author) & Ross, Z. K., 17 Dec 2020, In: PLoS Pathogens. 16, 12, 6 p., e1009094.

Research output: Contribution to journal › Article › peer-review

Open Access

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9 Citations (Scopus)

9 Downloads (Pure)

Catalase T-deficient fission yeast meiocytes show resistance to ionizing radiation

Muhtadi, R., Lorenz, A., Mpaulo, S., Siebenwirth, C. & Scherthan, H. (Corresponding Author), 30 Sept 2020, In: Antioxidants. 9, 9, 17 p., 881.

Research output: Contribution to journal › Article › peer-review

Open Access

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2 Citations (Scopus)

9 Downloads (Pure)

Intragenic meiotic recombination in Schizosaccharomyces pombe is sensitive to environmental temperature changes

Brown, S. D., Audoynaud, C. & Lorenz, A. (Corresponding Author), Jun 2020, In: Chromosome Research. 28, p. 195-207 13 p.

Research output: Contribution to journal › Article › peer-review

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10 Citations (Scopus)

10 Downloads (Pure)

Candida auris: The path of yeast resistance

Lorenz, A., Apr 2020, In: Research Outreach. 113, p. 138-141 4 p.

Research output: Contribution to journal › Comment/debate

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22 Downloads (Pure)

Pseudohyphal growth of the emerging pathogen Candida auris is triggered by genotoxic stress through the S phase checkpoint

Bravo Ruiz, G., Ross, Z. K., Gow, N. A. R. & Lorenz, A. (Corresponding Author), 11 Mar 2020, In: mSphere. 5, 2, 17 p., e00151-20.

Research output: Contribution to journal › Article › peer-review

Open Access

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61 Citations (Scopus)

33 Downloads (Pure)

2019

DNA sequence differences are determinants of meiotic recombination outcome

Brown, S. D., Mpaulo, S. J., Asogwa, M. N., Jézéquel, M., Whitby, M. C. & Lorenz, A. (Corresponding Author), 11 Nov 2019, In: Scientific Reports. 9, 10 p., 16446.

Research output: Contribution to journal › Article › peer-review

Open Access

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7 Citations (Scopus)

32 Downloads (Pure)

Rapid and extensive karyotype diversification in haploid clinical Candida auris isolates

Bravo Ruiz, G., Ross, Z. K., Schelenz, S., Gow, N. A. R. & Lorenz, A. (Corresponding Author), Oct 2019, In: Current Genetics. 65, 5, p. 1217-1228 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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43 Citations (Scopus)

37 Downloads (Pure)

Immediate visualization of recombination events and chromosome segregation defects in fission yeast meiosis

Li, D., Roca, M., Yuecel, R. & Lorenz, A. (Corresponding Author), Sept 2019, In: Chromosoma. 128, 3, p. 385-396 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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5 Citations (Scopus)

20 Downloads (Pure)

ABC Transporter Genes Show Upregulated Expression in Drug Resistant Clinical Isolates of Candida auris: a Genome-Wide Characterization of ATP-Binding Cassette (ABC) Transporter Genes

Wasi, M., Khandelwal, N. K., Moorhouse, A. J., Nair, R., Vishwakarma, P., Ruiz, G. B., Ross, Z. K., Lorenz, A., Rudramurthy, S. M., Chakrabarti, A., Lynn, A. M., Mondal, A. K., Gow, N. A. R. & Prasad, R. (Corresponding Author), 16 Jul 2019, In: Frontiers in Microbiology. 10, 16 p., 1445.

Research output: Contribution to journal › Article › peer-review

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57 Citations (Scopus)

14 Downloads (Pure)

2018

The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris

Junker, K., Bravo Ruiz, G., Lorenz, A., Walker, L., Gow, N. & Wendland, J. (Corresponding Author), 8 Oct 2018, In: Scientific Reports. 8, 5 p., 14959.

Research output: Contribution to journal › Article › peer-review

Open Access

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17 Citations (Scopus)

22 Downloads (Pure)

Genetic interactions between the chromosome axis-associated protein Hop1 and homologous recombination determinants in Schizosaccharomyces pombe

Brown, S. D., Jarosinska, O. D. & Lorenz, A. (Corresponding Author), Oct 2018, In: Current Genetics. 64, 5, p. 1089-1104 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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9 Citations (Scopus)

15 Downloads (Pure)

2017

Modulation of meiotic homologous recombination by DNA helicases

Lorenz, A., 4 May 2017, In: Yeast. 34, 5, p. 195-203 9 p.

Research output: Contribution to journal › Literature review › peer-review

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15 Citations (Scopus)

26 Downloads (Pure)

2016

Single-step marker switching in Schizosaccharomyces pombe using a lithium acetate transformation protocol

Brown, S. D. & Lorenz, A., 20 Dec 2016, In: Bio-protocol. 6, 24, 11 p., e2075.

Research output: Contribution to journal › Article › peer-review

Open Access

DNA double-strand break formation and repair in Tetrahymena meiosis

Loidl, J. & Lorenz, A., Jun 2016, In: Seminars in Cell & Developmental Biology. 54, p. 126-134 9 p.

Research output: Contribution to journal › Literature review › peer-review

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19 Citations (Scopus)

19 Downloads (Pure)

Meiotic chromosome mobility in fission yeast is resistant to environmental stress

Illner, D., Lorenz, A. & Scherthan, H., 14 Apr 2016, In: Scientific Reports. 6, p. 1-16 16 p., 24222.

Research output: Contribution to journal › Article › peer-review

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2 Citations (Scopus)

11 Downloads (Pure)

The RecQ DNA helicase Rqh1 constrains Exonuclease 1-dependent recombination at stalled replication forks

Osman, F., Ahn, J. S., Lorenz, A. & Whitby, M. C., 9 Mar 2016, In: Scientific Reports. 6, 13 p., 22837.

Research output: Contribution to journal › Article › peer-review

Open Access

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10 Citations (Scopus)

14 Downloads (Pure)

2015

New cassettes for single-step drug-resistance and prototrophic marker switching in fission yeast

Lorenz, A. (Corresponding Author), Dec 2015, In: Yeast. 32, 12, p. 703-710 8 p.

Research output: Contribution to journal › Article › peer-review

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12 Citations (Scopus)

19 Downloads (Pure)

2014

Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination

Lorenz, A., Mehats, A., Osman, F. & Whitby, M. C., 16 Dec 2014, In: Nucleic Acids Research. 42, 22, p. 13723-13735 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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21 Citations (Scopus)

15 Downloads (Pure)

2013

MHF1–2/CENP-S-X performs distinct roles in centromere metabolism and genetic recombination

Bhattacharjee, S., Osman, F., Feeney, L., Lorenz, A., Bryer, C. & Whitby, M. C., 11 Sept 2013, In: Open Biology. 13, 9, 14 p., 130102.

Research output: Contribution to journal › Article › peer-review

Open Access

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27 Citations (Scopus)

12 Downloads (Pure)

Slx8 removes Pli1-dependent protein-SUMO conjugates including SUMOylated Topoisomerase I to promote genome stability

Steinacher, R., Osman, F., Lorenz, A., Bryer, C. & Whitby, M. C., 6 Aug 2013, In: PloS ONE. 8, 8, 10 p., e71960.

Research output: Contribution to journal › Article › peer-review

Open Access

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15 Citations (Scopus)

14 Downloads (Pure)

2012

How not to get cross(ed): A novel role for FANCM orthologs in meiotic recombination

Lorenz, A. & Whitby, M. C., 15 Sept 2012, In: Cell Cycle. 11, 18, p. 3347-3348 2 p.

Research output: Contribution to journal › Editorial › peer-review

Open Access

3 Citations (Scopus)

The fission yeast FANCM ortholog directs non-crossover recombination during meiosis

Lorenz, A., Osman, F., Sun, W., Nandi, S., Steinacher, R. & Whitby, M. C., 22 Jun 2012, In: Science. 336, 6088, p. 1585-1588 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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88 Citations (Scopus)

13 Downloads (Pure)

Mug20, a novel protein associated with linear elements in fission yeast meiosis

Estreicher, A., Lorenz, A. & Loidl, J., 1 Apr 2012, In: Current Genetics. 58, 2, p. 119-127 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Citations (Scopus)

The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability

Steinacher, R., Osman, F., Dalgaard, J. Z., Lorenz, A. & Whitby, M. C., 15 Mar 2012, In: Genes & Development. 26, 6, p. 594-602 9 p.

Research output: Contribution to journal › Article › peer-review

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56 Citations (Scopus)

11 Downloads (Pure)

2011

Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier

Sofueva, S., Osman, F., Lorenz, A., Steinacher, R., Castagnetti, S., Ledesma, J. & Whitby, M. C., Aug 2011, In: Nucleic Acids Research. 39, 15, p. 6568-6584 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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49 Citations (Scopus)

17 Downloads (Pure)

A failure of meiotic chromosome segregation in a fbh1Δ mutant correlates with persistent Rad51-DNA associations

Sun, W., Lorenz, A., Osman, F. & Whitby, M. C., Mar 2011, In: Nucleic Acids Research. 39, 5, p. 1718-1731 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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13 Citations (Scopus)

13 Downloads (Pure)

2010

Roles of Hop1 and Mek1 in meiotic chromosome pairing and recombination partner choice in Schizosaccharomyces pombe

Latypov, V., Rothenberg, M., Lorenz, A., Octobre, G., Csutak, O., Lehmann, E., Loidl, J. & Kohli, J., Apr 2010, In: Molecular and Cellular Biology. 30, 7, p. 1570-1581 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

40 Citations (Scopus)

The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant

Lorenz, A., West, S. C. & Whitby, M. C., Apr 2010, In: Nucleic Acids Research. 38, 6, p. 1866-1873 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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48 Citations (Scopus)

15 Downloads (Pure)

2009

Fbh1 limits Rad51-dependent recombination at blocked replication forks

Lorenz, A., Osman, F., Folkyte, V., Sofueva, S. & Whitby, M. C., Sept 2009, In: Molecular and Cellular Biology. 29, 17, p. 4742-4756 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

57 Citations (Scopus)

Analysis of Schizosaccharomyces pombe meiosis by nuclear spreading

Loidl, J. & Lorenz, A., 1 Jan 2009, Meiosis: Volume 2 - Cytological Methods. Keeney, S. (ed.). Springer , p. 15-36 22 p. (Methods in Molecular Biology; vol. 558).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

16 Citations (Scopus)

49 Downloads (Pure)

2008

The FANCM ortholog Fml1 promotes recombination at stalled replication forks and limits crossing over during DNA double-strand break repair

Sun, W., Nandi, S., Osman, F., Ahn, J. S., Jakovleska, J., Lorenz, A. & Whitby, M. C., 10 Oct 2008, In: Molecular Cell. 32, 1, p. 118-128 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

131 Citations (Scopus)

The Rad52 homologs Rad22 and Rti1 of Schizosaccharomyces pombe are not essential for meiotic interhomolog recombination, but are required for meiotic intrachromosomal recombination and mating-type-related DNA repair

Octobre, G., Lorenz, A., Loidl, J. & Kohli, J., Apr 2008, In: Genetics. 178, 4, p. 2399-2412 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Citations (Scopus)

2006

Crossover promotion and prevention

Lorenz, A. & Whitby, M. C., 1 Aug 2006, In: Biochemical Society Transactions. 34, 4, p. 537-541 5 p.

Research output: Contribution to journal › Literature review › peer-review

15 Citations (Scopus)

22 Downloads (Pure)

Meiotic recombination proteins localize to linear elements in Schizosaccharomyces pombe

Lorenz, A., Estreicher, A., Loidl, J. & Kohli, J., Aug 2006, In: Chromosoma. 115, 4, p. 330-340 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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58 Citations (Scopus)

29 Downloads (Pure)

Yeast nuclear envelope subdomains with distinct abilities to resist membrane expansion

Campbell, J. L., Lorenz, A., Witkin, K. L., Hays, T., Loidl, J. & Cohen-Fix, O., 1 Apr 2006, In: Molecular Biology of the Cell. 17, 4, p. 1768-1778 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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80 Citations (Scopus)

12 Downloads (Pure)

2005

Differential activation of M26-containing meiotic recombination hot spots in Schizosaccharomyces pombe

Pryce, D. W., Smirnova, J. B., McFarlane, R. J., Lorenz, A. & Loidl, J., 1 May 2005, In: Genetics. 170, 1, p. 95-106 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Citations (Scopus)

2004

S. pombe meiotic linear elements contain proteins related to synaptonemal complex components

Lorenz, A., Wells, J. L., Pryce, D. W., Novatchkova, M., Eisenhaber, F., McFarlane, R. J. & Loidl, J., 1 Jul 2004, In: Journal of Cell Science. 117, 15, p. 3343-3351 9 p.

Research output: Contribution to journal › Article › peer-review

94 Citations (Scopus)

2003

Chromosome pairing does not contribute to nuclear architecture in vegetative yeast cells

Lorenz, A., Fuchs, J., Loidl, J. & Bürger, R., 1 Oct 2003, In: Eukaryotic Cell. 2, 5, p. 856-866 11 p.

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

2002

Spatial organisation and behaviour of the parental chromosome sets in the nuclei of Saccharomyces cerevisiae × S. paradoxus hybrids

Lorenz, A., Fuchs, J., Trelles-Sticken, E., Scherthan, H. & Loidl, J., 1 Oct 2002, In: Journal of Cell Science. 115, 19, p. 3829-3835 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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20 Citations (Scopus)

49 Downloads (Pure)

Chromosome associations in budding yeast caused by integrated tandemly repeated transgenes

Fuchs, J., Lorenz, A. & Loidl, J., 15 Mar 2002, In: Journal of Cell Science. 115, 6, p. 1213-1220 8 p.

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Alexander Lorenz

Research output

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