Research output per year
Research output per year
Personal profile
Research Profile
Fergal’s research focuses on the role of inflammation and interferon activation in ALS. His work involves a combination of wet-lab (experimental, histological) and dry-lab (literature-based& big-data) approaches to answer fundemental questions in ALS research.
Fergal obtained his PhD in Evolutionary Genetics from the University of Cambridge before undertaking postdoctoral work at the Institute of Evolutionary Biology at the University of Edinburgh. His past research has focused on the evolutionary genetics of antiviral immunity in invertebrate animal models, and the evolution of antiviral immunity across invertebrates.
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Collaborations and top research areas from the last five years
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Protein misfolding enteropathy predicts and prognosticates neurodegenerative disease years before symptom onset
Langerová, T., MacVicar, E., Press, R., Read, F. L., Piana, M., Murdoch, S., Innes, J., Wilson, J., Watson, A. J. M., Waldron, F. M., Ramsay, G. (Corresponding Author) & Gregory, J. M. (Corresponding Author), 19 Apr 2026, (E-pub ahead of print) In: Gastroenterology.Research output: Contribution to journal › Article › peer-review
Open Access -
Metabolic signatures of ferritin and TDP-43 co-pathology provide a mechanistic basis for stratified therapeutic approaches in ALS
Spence, H. (Corresponding Author), Read, F., Waldron, F. & Gregory, J. (Corresponding Author), 16 Mar 2026, bioRxiv.Research output: Working paper › Preprint
Open Access -
Genotype-specific interferon signatures in amyotrophic lateral sclerosis relate to disease severity
Carletta, O., Perfetto, C., Rifai, O. M., Manganelli, F., Waldron, F., Maniatis, T., Gregory, J. & Gerbino, V. (Corresponding Author), Feb 2026, In: Brain. 149, 2, p. 489-501 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus) -
Amygdala TDP-43 pathology is associated with behavioural dysfunction and ferritin accumulation in amyotrophic lateral sclerosis
Rifai, O. M., Waldron, F., O'shaughnessy, J., Read, F., Gilodi, M., Pastore, A., Shneider, N., Tartaglia, G. G., Zacco, E., Spence, H. (Corresponding Author) & Gregory, J. (Corresponding Author), 2026, In: Brain Communications. 8, 2, 14 p., fcag104.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Quantitative Profiling of Nanoscopic Protein Aggregates Reveals Specific Fingerprint of TDP-43-Positive Assemblies in Motor Neuron Disease
Cox, D. (Corresponding Author), Burke, M., Milani, S., White, M. A., Waldron, F. M., Böken, D., Lobanova, E., Sreedharan, J., Gregory, J. M. & Klenerman, D. (Corresponding Author), 27 Nov 2025, In: Advanced Science. 12, 44, 13 p., e05484.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure)
Activities
- 1 Public Engagement
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Developing tests to improve access to MND therapies
Waldron, F. (Speaker)
23 Sept 2025Activity: Disseminating Research › Public Engagement