Laurent Trembleau

1962

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55 Article
3 Patent
1 Chapter

Design and synthesis new indole-based aromatase/iNOS inhibitors with apoptotic antiproliferative activity
Al-Wahaibi, L. H., Abou-Zied, H. A., Abdelrahman, M. H., Morcoss, M. M., Trembleau, L. (Corresponding Author), Youssif, B. G. M. (Corresponding Author) & Bräse, S. (Corresponding Author), 6 Sept 2024, In: Frontiers in Chemistry. 12, 19 p., 1432920.
Research output: Contribution to journal › Article › peer-review

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13 Link opens in a new tab Citations (Scopus)

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Accraspiroketides A-B, Phenylnaphthacenoid-Derived Polyketides with Unprecedented [6+6+6+6]+[5+5] Spiro-Architecture
Maglangit, F. (Corresponding Author), Wang, S., Moser, A. (Corresponding Author), Kyeremeh, K., Trembleau, L., Zhou, Y., Clark, D. J., Tabudravu, J. & Deng, H., 26 Apr 2024, In: Journal of Natural Products. 87, 4, p. 831-836 6 p.
Research output: Contribution to journal › Article › peer-review
5 Link opens in a new tab Citations (Scopus)
Design, Synthesis, and Biological Evaluation of Indole-2-carboxamides as Potential Multi-Target Antiproliferative Agents
Al-Wahaibi, L. H., Mohammed, A. F., Abdelrahman, M. H., Trembleau, L. & Youssif, B. G. M., 22 Jul 2023, In: Pharmaceuticals. 16, 7, 23 p., 1039.
Research output: Contribution to journal › Article › peer-review

Open Access
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19 Link opens in a new tab Citations (Scopus)

8 Downloads (Pure)
Design, synthesis, apoptotic, and antiproliferative effects of 5-chloro-3- (2-methoxyvinyl)-indole-2-carboxamides and pyrido[3,4-b]indol-1-ones as potent EGFR^WT/EGFR^T790M inhibitors
Al-Wahaibi, L. H. (Corresponding Author), Mohammed, A. F., Abdel Rahman, F. E. Z. S., Abdelrahman, M. H., Gu, X., Trembleau, L. (Corresponding Author) & Youssif, B. G. M., 31 May 2023, In: Journal of enzyme inhibition and medicinal chemistry. 38, 1, 1 p., 2218602.
Research output: Contribution to journal › Article › peer-review

Open Access
File
18 Link opens in a new tab Citations (Scopus)

9 Downloads (Pure)
Discovery of new 5-substituted-indole-2-carboxamides as dual epidermal growth factor receptor (EGFR)/cyclin dependent kinase-2 (CDK2) inhibitors with potent antiproliferative action
Mohamed, F. A. M. (Corresponding Author), Alakilli, S. Y. M., El Azab, E. F., Baawad, F. A. M., Shaaban, E. I. A., Alrub, H. A., Hendawy, O., Gomaa, H. A. M., Bakr, A. G., Abdelrahman, M. H., Trembleau, L., Mohammed, A. F. & Youssif, B. G. M., 1 Apr 2023, In: RSC Medicinal Chemistry. 14, 4, p. 734-744 11 p.
Research output: Contribution to journal › Article › peer-review
12 Link opens in a new tab Citations (Scopus)

Crystal structures of four indole derivatives as possible cannabinoid allosteric antagonists: CCDC 1062392: Experimental Crystal Structure Determination
Kerr, J. R. (Contributor), Trembleau, L. A. C. (Contributor), Storey, J. M. D. (Contributor), Wardell, J. L. (Contributor) & Harrison, W. T. A. (Contributor), Cambridge Crystallographic Data Centre, 29 Apr 2015
DOI: 10.5517/cc14nhq0
Dataset
Crystal structures of four indole derivatives as possible cannabinoid allosteric antagonists: CCDC 1062391: Experimental Crystal Structure Determination
Kerr, J. R. (Contributor), Trembleau, L. A. C. (Contributor), Storey, J. M. D. (Contributor), Wardell, J. L. (Contributor) & Harrison, W. T. A. (Contributor), Cambridge Crystallographic Data Centre, 29 Apr 2015
DOI: 10.5517/cc14nhpz
Dataset
Crystal structures of four indole derivatives as possible cannabinoid allosteric antagonists: CCDC 1062390: Experimental Crystal Structure Determination
Kerr, J. R. (Contributor), Trembleau, L. A. C. (Contributor), Storey, J. M. D. (Contributor), Wardell, J. L. (Contributor) & Harrison, W. T. A. (Contributor), Cambridge Crystallographic Data Centre, 29 Apr 2015
DOI: 10.5517/cc14nhny
Dataset
Crystal structures of four indole derivatives as possible cannabinoid allosteric antagonists: CCDC 1062393: Experimental Crystal Structure Determination
Kerr, J. R. (Contributor), Trembleau, L. A. C. (Contributor), Storey, J. M. D. (Contributor), Wardell, J. L. (Contributor) & Harrison, W. T. A. (Contributor), Cambridge Crystallographic Data Centre, 29 Apr 2015
DOI: 10.5517/cc14nhr1
Dataset

Laurent Trembleau

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Collaborations and top research areas from the last five years

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Design and synthesis new indole-based aromatase/iNOS inhibitors with apoptotic antiproliferative activity

Accraspiroketides A-B, Phenylnaphthacenoid-Derived Polyketides with Unprecedented [6+6+6+6]+[5+5] Spiro-Architecture

Design, Synthesis, and Biological Evaluation of Indole-2-carboxamides as Potential Multi-Target Antiproliferative Agents

Design, synthesis, apoptotic, and antiproliferative effects of 5-chloro-3- (2-methoxyvinyl)-indole-2-carboxamides and pyrido[3,4-b]indol-1-ones as potent EGFR^WT/EGFR^T790M inhibitors

Discovery of new 5-substituted-indole-2-carboxamides as dual epidermal growth factor receptor (EGFR)/cyclin dependent kinase-2 (CDK2) inhibitors with potent antiproliferative action

Crystal structures of four indole derivatives as possible cannabinoid allosteric antagonists: CCDC 1062392: Experimental Crystal Structure Determination

Crystal structures of four indole derivatives as possible cannabinoid allosteric antagonists: CCDC 1062391: Experimental Crystal Structure Determination

Crystal structures of four indole derivatives as possible cannabinoid allosteric antagonists: CCDC 1062390: Experimental Crystal Structure Determination

Crystal structures of four indole derivatives as possible cannabinoid allosteric antagonists: CCDC 1062393: Experimental Crystal Structure Determination

Laurent Trembleau

Fingerprint

Collaborations and top research areas from the last five years

Research output

Datasets