Research output per year
Research output per year
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Dive into the research topics where Shinichiro Hiraga is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Checkpoint phosphorylation sites on budding yeast Rif1 protect nascent DNA from degradation by Sgs1-Dna2
Gali, V. K., Monerawela, C., Laksir, Y., Hiraga, S.-I. & Donaldson, A. D. (Corresponding Author), 1 Dec 2023, In: PLoS Genetics. 19, 11, 24 p., e1011044.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)6 Downloads (Pure) -
Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region
Balasubramanian, S., Andreani, M., Andrade, J. G., Saha, T., Sundaravinayagam, D., Garzón, J., Zhang, W., Popp, O., Hiraga, S.-I., Rahjouei, A., Rosen, D. B., Mertins, P., Chait, B. T., Donaldson, A. D. & Di Virgilio, M. (Corresponding Author), 13 Apr 2022, In: eLife. 11, 30 p., e75047.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)14 Downloads (Pure) -
SAF-A promotes origin licensing and replication fork progression to ensure robust DNA replication
Connolly, C., Takahashi, S., Miura, H., Hiratani, I., Gilbert, N., Donaldson, A. & Hiraga, S.-I. (Corresponding Author), 24 Jan 2022, In: Journal of Cell Science. 135, 2, 15 p., jcs.258991.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)16 Downloads (Pure) -
Protein phosphatase 1 acts as a RIF1 effector to suppress DSB resection prior to Shieldin action
Isobe, S.-Y., Hiraga, S.-I., Nagao, K., Sasanuma, H., Donaldson, A. D. & Obuse, C., 13 Jul 2021, In: Cell Reports. 36, 2, 18 p., 109383.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)17 Downloads (Pure) -
Replication timing maintains the global epigenetic state in human cells
Klein, K. N., Zhao, P. A., Lyu, X., Sasaki, T., Bartlett, D. A., Singh, A. M., Tasan, I., Zhang, M., Watts, L. P., Hiraga, S.-I., Natsume, T., Zhou, X., Baslan, T., Leung, D., Kanemaki, M. T., Donaldson, A. D., Zhao, H., Dalton, S., Corces, V. G. & Gilbert, D. M. (Corresponding Author), 23 Apr 2021, In: Science. 372, 6540, p. 371-378 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile87 Citations (Scopus)13 Downloads (Pure)
Datasets
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ChIP-Seq analysis of V5-tagged budding yeast Rif1
Hiraga, S. (Creator), EMBL-EBI, 19 Nov 2023
https://www.ebi.ac.uk/biostudies/arrayexpress/studies/E-MTAB-13452
Dataset
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Rif1 acts through Protein Phosphatase 1 and independent of replication timing to suppresses telomere extension in budding yeast
Kedziora, S. (Creator), Gali, V. (Creator), Wilson, R. (Creator), Clark, K. (Creator), Nieduszynski, C. A. (Creator), Hiraga, S. (Creator) & Donaldson, A. (Creator), GEO, 14 Feb 2018
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE109241
Dataset
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Single-cell replication timing analysis of hTERT-RPE1 cells depleted for SAF-A protein
Hiraga, S. (Creator), EMBL-EBI, 15 Dec 2021
https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-10234/
Dataset
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ChIP-Seq analysis of Myc-tagged budding yeast Rif1
Hiraga, S. (Creator), EMBL-EBI, 19 Nov 2023
https://www.ebi.ac.uk/biostudies/arrayexpress/studies/E-MTAB-13451
Dataset
Activities
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Requirement for SAF-A/HNRNPU in establishing an open chromatin structure needed for multiple steps in DNA replication
Hiraga, S. (Speaker)
9 Sept 2021Activity: Disseminating Research › Presentation
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Chromatin-organising protein SAF-A is required for robust DNA replication
Hiraga, S. (Speaker)
26 Mar 2021Activity: Disseminating Research › Workshop, Seminar or Course
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DNA (Journal)
Hiraga, S. (Peer Review)
2021 → …Activity: Publication peer-review and editorial work › Editor of research journal / publication series
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SAF-A is required for normal DNA replication via creating open chromatin
Hiraga, S. (Speaker)
Oct 2021Activity: Disseminating Research › Presentation
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RIF1 protein protects chromosome integrity from DNA replication stress at multiple points
Hiraga, S. (Speaker)
17 Jul 2019Activity: Disseminating Research › Invited talk