60th forum in immunology: General discussion

D. J. Blackbourn

60th forum in immunology: General discussion

D. J. Blackbourn

Medical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Th1/Th2 cytokines in AIDS: sorting out the confusion: D.J. Blackbourn, Page 715

The type I/type 2 cytokine balance concept may help to account, at least in part, for the immunopathogenesis of AIDS. Type 1 cytokines are suggested by Clerici and Shearer (this Forum) to prevent CD4 ÷ cell loss and dysfunction by programmed cell death (PCD) and type 2 cytokines enhance PCD. However, the type 1/type 2 cytokine profile relationship and its involvement in disease progression in HIV-
infected individuals is incompletely understood.

Original language	English
Pages (from-to)	714-724 (715)
Number of pages	1
Journal	Research in Immunology
Volume	145
Issue number	8-9
Publication status	Published - 1994

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

AIDS
Cytokine
Forum
HIV
Macrophage
Pathogenesis
Regulation
T lymphocyte

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https://www.sciencedirect.com/journal/research-in-immunology/vol/145/issue/8

Cite this

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title = "60th forum in immunology: General discussion",

abstract = "Th1/Th2 cytokines in AIDS: sorting out the confusion: D.J. Blackbourn, Page 715 The type I/type 2 cytokine balance concept may help to account, at least in part, for the immunopathogenesis of AIDS. Type 1 cytokines are suggested by Clerici and Shearer (this Forum) to prevent CD4 ÷ cell loss and dysfunction by programmed cell death (PCD) and type 2 cytokines enhance PCD. However, the type 1/type 2 cytokine profile relationship and its involvement in disease progression in HIV- infected individuals is incompletely understood.",

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AB - Th1/Th2 cytokines in AIDS: sorting out the confusion: D.J. Blackbourn, Page 715 The type I/type 2 cytokine balance concept may help to account, at least in part, for the immunopathogenesis of AIDS. Type 1 cytokines are suggested by Clerici and Shearer (this Forum) to prevent CD4 ÷ cell loss and dysfunction by programmed cell death (PCD) and type 2 cytokines enhance PCD. However, the type 1/type 2 cytokine profile relationship and its involvement in disease progression in HIV- infected individuals is incompletely understood.

KW - AIDS

KW - Cytokine

KW - Forum

KW - HIV

KW - Macrophage

KW - Pathogenesis

KW - Regulation

KW - T lymphocyte

UR - https://www.scopus.com/pages/publications/0028582114

M3 - Article

AN - SCOPUS:0028582114

SN - 0923-2494

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SP - 714-724 (715)

JO - Research in Immunology

JF - Research in Immunology

IS - 8-9

ER -

60th forum in immunology: General discussion

Abstract

UN SDGs

Keywords

Access to Document

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