The ability to use clinical and research data at scale is central to hopes for data-driven medicine. However, in using such data researchers often encounter hurdles–both technical, such as differing data security requirements, and social, such as the terms of informed consent, legal requirements and patient and public trust. Federated or distributed data networks have been proposed and adopted in response to these hurdles. However, to date there has been little consideration of how FDNs respond to both technical and social constraints on data use. In this Perspective we propose an approach to thinking about data in terms that make it easier to navigate the health data space and understand the value of differing approaches to data collection, storage and sharing. We set out a socio-technical model of data systems that we call the “Concentric Circles View” (CCV) of data-relationships. The aim is to enable a consistent understanding of the fit between the local relationships within which data are produced and the extended socio-technical systems that enable their use. The paper suggests this model can help understand and tackle challenges associated with the use of real-world data in the health setting. We use the model to understand not only how but why federated networks may be well placed to address emerging issues and adapt to the evolving needs of health research for patient benefit. We conclude that the CCV provides a useful model with broader application in mapping, understanding, and tackling the major challenges associated with using real world data in the health setting.
Bibliographical noteFunding Information:
This work was funded by the European Union's Horizon 2020 research and innovation programme and EFPIA, Grant number 806968. RM's contribution was also supported by Wellcome Trust Grant number 108413/A/15/D. The APC was funded by Janssen Research and Development, LLC. MS is grateful for the support of the Oxford NIHR Biomedical Research Centre.
Data Availability StatementThe original contributions presented in the study are
included in the article/supplementary material, further inquiries
can be directed to the corresponding author.
- distributed data access
- federated data access