A long-term dose-response study of mitomycin in glaucoma filtration surgery

A L Robin, R Ramakrishnan, R Krishnadas, S D Smith, J D Katz, S Selvaraj, G L Skuta, R Bhatnagar, Selvaraj Sivasubramaniam

Research output: Contribution to journalArticlepeer-review

125 Citations (Scopus)


To establish the long-term, dose-response relationship between the concentration of and duration of exposure to mitomycin to a decrease in intraocular pressure (IOP) and fewer complications.
Original languageEnglish
Pages (from-to)969-74
Number of pages6
JournalArchives of Ophthalmology
Issue number8
Publication statusPublished - Aug 1997


  • Antibiotics, Antineoplastic
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Female
  • Glaucoma, Angle-Closure
  • Glaucoma, Open-Angle
  • Humans
  • Intraocular Pressure
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Mitomycin
  • Ophthalmic Solutions
  • Postoperative Complications
  • Prospective Studies
  • Time Factors
  • Trabeculectomy
  • Treatment Outcome
  • Visual Acuity


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