Anterior cruciate ligament integrity in osteoarthritis of the knee in patients undergoing total knee replacement

M J M Douglas, J D Hutchison, A G Sutherland

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24 Citations (Scopus)


Anterior cruciate ligament (ACL) rupture has been implicated in the development of knee osteoarthritis (OA). This study aimed at determining the incidence of prior ACL deficiency in patients undergoing total knee replacement (TKR), the effect of prior ACL deficiency on function and the macroscopic and microscopic appearance of the ligament.
Materials and methods
A total of 95 patients undergoing elective TKR for OA were recruited. Pre-operative knee assessment included questionnaires and KT1000 testing. The ACL was examined macroscopically at TKR in all patients, and 10 ACL specimens were examined histologically.
The ACL was absent in 12% of the patients. There was no significant correlation between the pre-operative assessment or function and operative findings. The ACL samples all demonstrated degenerative change of varying severities.
ACL deficiency is uncommon in patients undergoing TKR for OA, and does not worsen pre-operative function.
Original languageEnglish
Pages (from-to)149-154
Number of pages6
JournalJournal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology
Issue number3
Publication statusPublished - Sept 2010


  • age factors
  • aged
  • aged, 80 and over
  • analysis of variance
  • anterior cruciate ligament
  • arthroplasty, replacement, knee
  • cohort studies
  • confidence intervals
  • female
  • humans
  • joint instability
  • male
  • middle aged
  • osteoarthritis, knee
  • pain measurement
  • physical examination
  • preoperative care
  • range of motion, articular
  • recovery of function
  • reference values
  • risk assessment
  • rupture
  • severity of illness index
  • sex factors
  • surgical procedures, elective
  • treatment outcome


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