Anticancer effects of bioactive berry compounds

Florence Folmer; Umesh Basavaraju; Marcel Jaspars; Georgina Hold; Emad El-Omar; Mario Dicato; Marc Diederich

doi:10.1007/s11101-013-9319-z

Anticancer effects of bioactive berry compounds

Florence Folmer, Umesh Basavaraju, Marcel Jaspars, Georgina Hold, Emad El-Omar, Mario Dicato, Marc Diederich^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

90 Citations (Scopus)

Abstract

In the present review, we describe chemical and chemopreventive properties as well as health benefits of both extracts and bioactive compounds from various types of berries including small soft-fleshed edible berries and from berry-like fruits such as strawberries, raspberries, blackberries, blueberries, mulberries, currants, gooseberries, elderberries, a double dagger ai berries, and pomegranates. In particular, we describe how berry-derided phytochemicals, including anthocyanidins, proanthocyanidins, flavonols, flavanols, stilbenoids, terpenoids, ellagitannins, and ellagic acid target oxidative and UV radiation stress-induced DNA damage, Helicobacter pilori infection, pro-inflammatory as well as the major cancer hallmarks.

Original language	English
Pages (from-to)	295-322
Number of pages	28
Journal	Phytochemistry reviews
Volume	13
Issue number	1
Early online date	5 Sept 2013
DOIs	https://doi.org/10.1007/s11101-013-9319-z
Publication status	Published - 1 Mar 2014

Bibliographical note

Acknowledgments Research at the Laboratoire de Biologie Mole´culaire et Cellulaire du Cancer (LBMCC) is financially supported by ‘‘Recherche Cancer et Sang’’ foundation, by «Recherches Scientifiques Luxembourg» asbl, by «Een Ha¨erz fir Kriibskrank Kanner» association, the Action Lions ‘‘Vaincre le Cancer’’ Luxembourg, The Fonds National de la Recherche Luxembourg, Televie Luxembourg and the Foundation for Scientific Cooperation between Germany and Luxemburg is thanked for additional support. Further support was received from the European Union (ITN ‘‘RedCat’’ 215009 and Interreg IVa project ‘‘Corena’’). MD is supported by the National Research Foundation (NRF) by the MEST of Korea for Tumor Microenvironment Global Core Research Center (GCRC) grant, [Grant Number 2012-0001184]; by the Seoul National University Research grant and by the Research Settlement Fund for the new faculty of SNU.

Keywords

anthocyanin
anti-cancer
anti-inflammatory
anti-oxidant
berry
flavonoid
NF-Kappa-B
colon-cancer cells
tumor-necrosis-factor
punica-granatum-L.
antioxidant capacity
prostate-cancer
in-vitro
black-raspberry
TNF-Alpha
anthocyanin-rich

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s11101-013-9319-z

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title = "Anticancer effects of bioactive berry compounds",

abstract = "In the present review, we describe chemical and chemopreventive properties as well as health benefits of both extracts and bioactive compounds from various types of berries including small soft-fleshed edible berries and from berry-like fruits such as strawberries, raspberries, blackberries, blueberries, mulberries, currants, gooseberries, elderberries, a double dagger ai berries, and pomegranates. In particular, we describe how berry-derided phytochemicals, including anthocyanidins, proanthocyanidins, flavonols, flavanols, stilbenoids, terpenoids, ellagitannins, and ellagic acid target oxidative and UV radiation stress-induced DNA damage, Helicobacter pilori infection, pro-inflammatory as well as the major cancer hallmarks.",

keywords = "anthocyanin, anti-cancer, anti-inflammatory, anti-oxidant, berry, flavonoid, NF-Kappa-B, colon-cancer cells, tumor-necrosis-factor, punica-granatum-L., antioxidant capacity, prostate-cancer, in-vitro, black-raspberry, TNF-Alpha, anthocyanin-rich",

author = "Florence Folmer and Umesh Basavaraju and Marcel Jaspars and Georgina Hold and Emad El-Omar and Mario Dicato and Marc Diederich",

note = "Acknowledgments Research at the Laboratoire de Biologie Mole´culaire et Cellulaire du Cancer (LBMCC) is financially supported by {\textquoteleft}{\textquoteleft}Recherche Cancer et Sang{\textquoteright}{\textquoteright} foundation, by «Recherches Scientifiques Luxembourg» asbl, by «Een Ha¨erz fir Kriibskrank Kanner» association, the Action Lions {\textquoteleft}{\textquoteleft}Vaincre le Cancer{\textquoteright}{\textquoteright} Luxembourg, The Fonds National de la Recherche Luxembourg, Televie Luxembourg and the Foundation for Scientific Cooperation between Germany and Luxemburg is thanked for additional support. Further support was received from the European Union (ITN {\textquoteleft}{\textquoteleft}RedCat{\textquoteright}{\textquoteright} 215009 and Interreg IVa project {\textquoteleft}{\textquoteleft}Corena{\textquoteright}{\textquoteright}). MD is supported by the National Research Foundation (NRF) by the MEST of Korea for Tumor Microenvironment Global Core Research Center (GCRC) grant, [Grant Number 2012-0001184]; by the Seoul National University Research grant and by the Research Settlement Fund for the new faculty of SNU.",

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doi = "10.1007/s11101-013-9319-z",

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AU - Basavaraju, Umesh

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AU - El-Omar, Emad

AU - Dicato, Mario

AU - Diederich, Marc

N1 - Acknowledgments Research at the Laboratoire de Biologie Mole´culaire et Cellulaire du Cancer (LBMCC) is financially supported by ‘‘Recherche Cancer et Sang’’ foundation, by «Recherches Scientifiques Luxembourg» asbl, by «Een Ha¨erz fir Kriibskrank Kanner» association, the Action Lions ‘‘Vaincre le Cancer’’ Luxembourg, The Fonds National de la Recherche Luxembourg, Televie Luxembourg and the Foundation for Scientific Cooperation between Germany and Luxemburg is thanked for additional support. Further support was received from the European Union (ITN ‘‘RedCat’’ 215009 and Interreg IVa project ‘‘Corena’’). MD is supported by the National Research Foundation (NRF) by the MEST of Korea for Tumor Microenvironment Global Core Research Center (GCRC) grant, [Grant Number 2012-0001184]; by the Seoul National University Research grant and by the Research Settlement Fund for the new faculty of SNU.

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N2 - In the present review, we describe chemical and chemopreventive properties as well as health benefits of both extracts and bioactive compounds from various types of berries including small soft-fleshed edible berries and from berry-like fruits such as strawberries, raspberries, blackberries, blueberries, mulberries, currants, gooseberries, elderberries, a double dagger ai berries, and pomegranates. In particular, we describe how berry-derided phytochemicals, including anthocyanidins, proanthocyanidins, flavonols, flavanols, stilbenoids, terpenoids, ellagitannins, and ellagic acid target oxidative and UV radiation stress-induced DNA damage, Helicobacter pilori infection, pro-inflammatory as well as the major cancer hallmarks.

AB - In the present review, we describe chemical and chemopreventive properties as well as health benefits of both extracts and bioactive compounds from various types of berries including small soft-fleshed edible berries and from berry-like fruits such as strawberries, raspberries, blackberries, blueberries, mulberries, currants, gooseberries, elderberries, a double dagger ai berries, and pomegranates. In particular, we describe how berry-derided phytochemicals, including anthocyanidins, proanthocyanidins, flavonols, flavanols, stilbenoids, terpenoids, ellagitannins, and ellagic acid target oxidative and UV radiation stress-induced DNA damage, Helicobacter pilori infection, pro-inflammatory as well as the major cancer hallmarks.

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KW - tumor-necrosis-factor

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KW - antioxidant capacity

KW - prostate-cancer

KW - in-vitro

KW - black-raspberry

KW - TNF-Alpha

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EP - 322

JO - Phytochemistry reviews

JF - Phytochemistry reviews

IS - 1

ER -

Anticancer effects of bioactive berry compounds

Abstract

Bibliographical note

Keywords

UN SDGs

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