Anticancer effects of bioactive berry compounds

Florence Folmer, Umesh Basavaraju, Marcel Jaspars, Georgina Hold, Emad El-Omar, Mario Dicato, Marc Diederich*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

90 Citations (Scopus)


In the present review, we describe chemical and chemopreventive properties as well as health benefits of both extracts and bioactive compounds from various types of berries including small soft-fleshed edible berries and from berry-like fruits such as strawberries, raspberries, blackberries, blueberries, mulberries, currants, gooseberries, elderberries, a double dagger ai berries, and pomegranates. In particular, we describe how berry-derided phytochemicals, including anthocyanidins, proanthocyanidins, flavonols, flavanols, stilbenoids, terpenoids, ellagitannins, and ellagic acid target oxidative and UV radiation stress-induced DNA damage, Helicobacter pilori infection, pro-inflammatory as well as the major cancer hallmarks.

Original languageEnglish
Pages (from-to)295-322
Number of pages28
JournalPhytochemistry reviews
Issue number1
Early online date5 Sept 2013
Publication statusPublished - 1 Mar 2014

Bibliographical note

Acknowledgments Research at the Laboratoire de Biologie Mole´culaire et Cellulaire du Cancer (LBMCC) is financially supported by ‘‘Recherche Cancer et Sang’’ foundation, by «Recherches Scientifiques Luxembourg» asbl, by «Een Ha¨erz fir Kriibskrank Kanner» association, the Action Lions ‘‘Vaincre le Cancer’’ Luxembourg, The Fonds National de la Recherche Luxembourg, Televie Luxembourg and the Foundation for Scientific Cooperation between Germany and Luxemburg is thanked for additional support. Further support was received from the European Union (ITN ‘‘RedCat’’ 215009 and Interreg IVa project ‘‘Corena’’). MD is supported by the National Research Foundation (NRF) by the MEST of Korea for Tumor Microenvironment Global Core Research Center (GCRC) grant, [Grant Number 2012-0001184]; by the Seoul National University Research grant and by the Research Settlement Fund for the new faculty of SNU.


  • anthocyanin
  • anti-cancer
  • anti-inflammatory
  • anti-oxidant
  • berry
  • flavonoid
  • NF-Kappa-B
  • colon-cancer cells
  • tumor-necrosis-factor
  • punica-granatum-L.
  • antioxidant capacity
  • prostate-cancer
  • in-vitro
  • black-raspberry
  • TNF-Alpha
  • anthocyanin-rich


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