Apolipoprotein E gene in Parkinson's disease, Lewy body dementia and Alzheimer's disease

D. St. Clair

Apolipoprotein E gene in Parkinson's disease, Lewy body dementia and Alzheimer's disease

D. St. Clair^*

^*Corresponding author for this work

Applied Medicine

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Apolipoprotein E (Apo E) epsilon 4 allele is a risk factor for early and late onset Alzheimer's disease. This prompted us to examine other neurophyschiatric phenotypes. Epsilon 4 allele was significantly enriched in Lewy body dementia (N = 39) but not in Parkinson's disease (n = 50) or Schizophrenia (n = 175) compared to aged non-demented controls (n = 47) and the Scottish population (n = 400). We conclude that Lewy body disease should be regarded as a variant of Alzheimer's but not Parkinson's disease.

Original language	English
Pages (from-to)	161-165
Number of pages	5
Journal	Journal of Neural Transmission, Supplement
Issue number	51
Publication status	Published - 1 Feb 1997

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cite this

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title = "Apolipoprotein E gene in Parkinson's disease, Lewy body dementia and Alzheimer's disease",

abstract = "Apolipoprotein E (Apo E) epsilon 4 allele is a risk factor for early and late onset Alzheimer's disease. This prompted us to examine other neurophyschiatric phenotypes. Epsilon 4 allele was significantly enriched in Lewy body dementia (N = 39) but not in Parkinson's disease (n = 50) or Schizophrenia (n = 175) compared to aged non-demented controls (n = 47) and the Scottish population (n = 400). We conclude that Lewy body disease should be regarded as a variant of Alzheimer's but not Parkinson's disease.",

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AU - St. Clair, D.

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N2 - Apolipoprotein E (Apo E) epsilon 4 allele is a risk factor for early and late onset Alzheimer's disease. This prompted us to examine other neurophyschiatric phenotypes. Epsilon 4 allele was significantly enriched in Lewy body dementia (N = 39) but not in Parkinson's disease (n = 50) or Schizophrenia (n = 175) compared to aged non-demented controls (n = 47) and the Scottish population (n = 400). We conclude that Lewy body disease should be regarded as a variant of Alzheimer's but not Parkinson's disease.

AB - Apolipoprotein E (Apo E) epsilon 4 allele is a risk factor for early and late onset Alzheimer's disease. This prompted us to examine other neurophyschiatric phenotypes. Epsilon 4 allele was significantly enriched in Lewy body dementia (N = 39) but not in Parkinson's disease (n = 50) or Schizophrenia (n = 175) compared to aged non-demented controls (n = 47) and the Scottish population (n = 400). We conclude that Lewy body disease should be regarded as a variant of Alzheimer's but not Parkinson's disease.

UR - https://www.scopus.com/pages/publications/0031283225

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JO - Journal of Neural Transmission, Supplement

JF - Journal of Neural Transmission, Supplement

IS - 51

ER -

Apolipoprotein E gene in Parkinson's disease, Lewy body dementia and Alzheimer's disease

Abstract

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