Association of CCR5 del 32 with reduced risk of asthma

I P  Hall; A  Wheatley; G  Christie; C  McDougall; R  Hubbard; P J  Helms

Association of CCR5 del 32 with reduced risk of asthma

I P Hall, A Wheatley, G Christie, C McDougall, R Hubbard, P J Helms

Applied Health Sciences

Research output: Contribution to journal › Article

97 Citations (Web of Science)

Abstract

We report that Individuals carrying the CCR5 Delta 32 mutation, a naturally occurring variant of the C-C chemokine receptor 5 (CCR5), are at reduced risk of developing asthma, These data suggest a possible explanation for the high prevalence of this mutation in the general population.

Original language	English
Pages (from-to)	1264-1265
Number of pages	2
Journal	The Lancet
Volume	354
Publication status	Published - 1999

Keywords

HIV-1 INFECTION
CHEMOKINES
GENE

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Association of CCR5 del 32 with reduced risk of asthma",

abstract = "We report that Individuals carrying the CCR5 Delta 32 mutation, a naturally occurring variant of the C-C chemokine receptor 5 (CCR5), are at reduced risk of developing asthma, These data suggest a possible explanation for the high prevalence of this mutation in the general population.",

keywords = "HIV-1 INFECTION, CHEMOKINES, GENE",

author = "Hall, {I P} and A Wheatley and G Christie and C McDougall and R Hubbard and Helms, {P J}",

year = "1999",

language = "English",

volume = "354",

pages = "1264--1265",

journal = "The Lancet",

issn = "0140-6736",

publisher = "ACADEMIC PRESS INC ELSEVIER SCIENCE",

}

TY - JOUR

T1 - Association of CCR5 del 32 with reduced risk of asthma

AU - Hall, I P

AU - Wheatley, A

AU - Christie, G

AU - McDougall, C

AU - Hubbard, R

AU - Helms, P J

PY - 1999

Y1 - 1999

N2 - We report that Individuals carrying the CCR5 Delta 32 mutation, a naturally occurring variant of the C-C chemokine receptor 5 (CCR5), are at reduced risk of developing asthma, These data suggest a possible explanation for the high prevalence of this mutation in the general population.

AB - We report that Individuals carrying the CCR5 Delta 32 mutation, a naturally occurring variant of the C-C chemokine receptor 5 (CCR5), are at reduced risk of developing asthma, These data suggest a possible explanation for the high prevalence of this mutation in the general population.

KW - HIV-1 INFECTION

KW - CHEMOKINES

KW - GENE

M3 - Article

SN - 0140-6736

VL - 354

SP - 1264

EP - 1265

JO - The Lancet

JF - The Lancet

ER -

Association of CCR5 del 32 with reduced risk of asthma

Abstract

Keywords

UN SDGs

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