Previous studies have found an association between chronic kidney disease and poor outcomes in stroke patients. However,
there is a paucity of literature evaluating this association by stroke type. We therefore aimed to explore the association
between CKD and stroke outcomes according to type of stroke. The data consisting of 594,681 stroke patients were acquired
from Universal Coverage Health Security Insurance Scheme Database in Thailand. Binary logistic regression was used to
assess the relationship of CKD and outcomes, which were as follows; in-hospital mortality, long length of stay (>3 days),
pneumonia, sepsis, respiratory failure and myocardial infarction. Results: after fully adjusting for covariates, CKD was associated with increased odds of in-hospital mortality in patients with ischemic (OR 1.32; 95% CI=1.27–1.38), haemorrhagic
(OR 1.31; 95% CI=1.24–1.39), and other undetermined stroke type (OR 1.44; 95% CI=1.21–1.73). CKD was found to
be associated with increased odds of pneumonia, sepsis, respiratory failure and myocardial infarction in ischaemic stroke.
While CKD was found to be associated with increase odds of sepsis, respiratory failure, and myocardial infarction, decrease
odds of pneumonia was observed in patients with haemorrhagic stroke. In other undetermined stroke type, CKD was found
to only be associated with increase odds of sepsis and respiratory failure, while there is no signifcant association of CKD
and increase or decrease odds with pneumonia and myocardial infarction. CKD was associated with poor outcomes in all
stroke types. CKD should be considered as part of stroke prognosis as well as identifying at risk patient population for inhospital complications.
Open Access via the Springer Compact Agreement
IMT received the Aberdeen Summer Research Scholarship as part of Aberdeen Clinical Academic Training and Development Scheme, University of Aberdeen, to carry out the research.
Funding (information that explains whether and by whom the research was supported).
- chronic kidney disease
- stroke type