Crystal structure of 3-(morpholin-4-yl)-1-phenyl-3-(pyridin-2-yl)propan-1-one

F M M Ahamed; M S A Padusha; B. Gunasekaran; W. T A Harrison

doi:10.1107/S2056989014026292

Crystal structure of 3-(morpholin-4-yl)-1-phenyl-3-(pyridin-2-yl)propan-1-one

F M M Ahamed, M S A Padusha, B. Gunasekaran^*, W. T A Harrison (Editor)

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

7 Downloads (Pure)

Abstract

In the title compound C₁₈H₂₀N₂O₂, the morpholine ring adopts a chair conformation with the exocyclic N - C bond in an equatorial orientation. The N atom of the morpholine ring and the C atom of the carbonyl group are in an anti conformation about the central C - C bond [torsion angle = - 162.92 (11)°] and the dihedral angle between the planes of the benzene ring and the pyridine ring is 83.30 (5)°. In the crystal, pairs of very weak C - H⋯π interactions link the molecules into inversion dimers.

Original language	English
Pages (from-to)	o24-o25
Number of pages	2
Journal	Acta Crystallographica Section E: Structure Reports Online
Volume	71
Issue number	1
Early online date	1 Jan 2015
DOIs	https://doi.org/10.1107/S2056989014026292
Publication status	Published - 1 Jan 2015

Bibliographical note

Acknowledgements
FMMA acknowledges the PG and Research Department of Chemistry and the Management of Jamal Mohamed College (Autonomous) for their kind support.

Keywords

Biological activity
Crystal structure
Morpholin-4-yl
Propan-1-one
Pyridin-2-yl

Access to Document

10.1107/S2056989014026292Licence: CC BY

Crystal structure 3-(morpholin-4-yl)-1-phenyl-3-(pyridin-2-yl)propan-1-one
© 2015 Ahamedet al. Licence: Creative Commons Attribution (CC-BY) https://creativecommons.org/licenses/by/4.0/
Final published version, 204 KBLicence: CC BY

Cite this

@article{74fb6b05a27d46f6b1b9cbb3fccd9661,

title = "Crystal structure of 3-(morpholin-4-yl)-1-phenyl-3-(pyridin-2-yl)propan-1-one",

abstract = "In the title compound C18H20N2O2, the morpholine ring adopts a chair conformation with the exocyclic N - C bond in an equatorial orientation. The N atom of the morpholine ring and the C atom of the carbonyl group are in an anti conformation about the central C - C bond [torsion angle = - 162.92 (11)°] and the dihedral angle between the planes of the benzene ring and the pyridine ring is 83.30 (5)°. In the crystal, pairs of very weak C - H⋯π interactions link the molecules into inversion dimers.",

keywords = "Biological activity, Crystal structure, Morpholin-4-yl, Propan-1-one, Pyridin-2-yl",

author = "Ahamed, {F M M} and Padusha, {M S A} and B. Gunasekaran and Harrison, {W. T A}",

note = "Acknowledgements FMMA acknowledges the PG and Research Department of Chemistry and the Management of Jamal Mohamed College (Autonomous) for their kind support.",

year = "2015",

month = jan,

day = "1",

doi = "10.1107/S2056989014026292",

language = "English",

volume = "71",

pages = "o24--o25",

journal = "Acta Crystallographica Section E: Structure Reports Online",

issn = "1600-5368",

publisher = "International Union of Crystallography",

number = "1",

}

TY - JOUR

T1 - Crystal structure of 3-(morpholin-4-yl)-1-phenyl-3-(pyridin-2-yl)propan-1-one

AU - Ahamed, F M M

AU - Padusha, M S A

AU - Gunasekaran, B.

A2 - Harrison, W. T A

N1 - Acknowledgements FMMA acknowledges the PG and Research Department of Chemistry and the Management of Jamal Mohamed College (Autonomous) for their kind support.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - In the title compound C18H20N2O2, the morpholine ring adopts a chair conformation with the exocyclic N - C bond in an equatorial orientation. The N atom of the morpholine ring and the C atom of the carbonyl group are in an anti conformation about the central C - C bond [torsion angle = - 162.92 (11)°] and the dihedral angle between the planes of the benzene ring and the pyridine ring is 83.30 (5)°. In the crystal, pairs of very weak C - H⋯π interactions link the molecules into inversion dimers.

AB - In the title compound C18H20N2O2, the morpholine ring adopts a chair conformation with the exocyclic N - C bond in an equatorial orientation. The N atom of the morpholine ring and the C atom of the carbonyl group are in an anti conformation about the central C - C bond [torsion angle = - 162.92 (11)°] and the dihedral angle between the planes of the benzene ring and the pyridine ring is 83.30 (5)°. In the crystal, pairs of very weak C - H⋯π interactions link the molecules into inversion dimers.

KW - Biological activity

KW - Crystal structure

KW - Morpholin-4-yl

KW - Propan-1-one

KW - Pyridin-2-yl

UR - http://www.scopus.com/inward/record.url?scp=84928159590&partnerID=8YFLogxK

U2 - 10.1107/S2056989014026292

DO - 10.1107/S2056989014026292

M3 - Article

AN - SCOPUS:84928159590

SN - 1600-5368

VL - 71

SP - o24-o25

JO - Acta Crystallographica Section E: Structure Reports Online

JF - Acta Crystallographica Section E: Structure Reports Online

IS - 1

ER -

Crystal structure of 3-(morpholin-4-yl)-1-phenyl-3-(pyridin-2-yl)propan-1-one

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this