Design, construction and use of a large-sample field-cycled PEDRI imager

David J. Lurie; Margaret A. Foster; David Yeung; James M S Hutchison

doi:10.1088/0031-9155/43/7/008

Design, construction and use of a large-sample field-cycled PEDRI imager

David J. Lurie^*
, Margaret A. Foster
, David Yeung
, James M S Hutchison

^*Corresponding author for this work

University of Aberdeen
Chinese University of Hong Kong

Research output: Contribution to journal › Article › peer-review

73 Citations (Scopus)

Abstract

The design, construction and use of a large-scale field-cycled proton- electron double-resonance imaging (FC-PEDRI) imager is described. The imager is based on a whole-body sized, vertical field, 59 mT permanent magnet. Field cycling is accomplished by the field compensation method, and uses a secondary, resistive magnet with an internal diameter of 52 cm. The magnetic field can be switched from zero to 59 mT or vice versa in 40 ms. It is used with a double-resonance coil assembly (NMR/EPR) comprising a solenoidal NMR transmit/receive coil and a coaxial, external birdcage resonator for EPR irradiation. Experiments to image the distribution of an exogenous nitroxide free radical in anaesthetized rabbits are described.

Original language	English
Pages (from-to)	1877-1886
Number of pages	10
Journal	Physics in Medicine and Biology
Volume	43
Issue number	7
DOIs	https://doi.org/10.1088/0031-9155/43/7/008
Publication status	Published - 30 Jul 1998

Bibliographical note

We thank Mr E Stevenson, Mr P Mullen and Mr J Carney for help in the construction of the screened room. This work was funded by the Medical Research Council and by the University of Aberdeen.

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10.1088/0031-9155/43/7/008

Cite this

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title = "Design, construction and use of a large-sample field-cycled PEDRI imager",

abstract = "The design, construction and use of a large-scale field-cycled proton- electron double-resonance imaging (FC-PEDRI) imager is described. The imager is based on a whole-body sized, vertical field, 59 mT permanent magnet. Field cycling is accomplished by the field compensation method, and uses a secondary, resistive magnet with an internal diameter of 52 cm. The magnetic field can be switched from zero to 59 mT or vice versa in 40 ms. It is used with a double-resonance coil assembly (NMR/EPR) comprising a solenoidal NMR transmit/receive coil and a coaxial, external birdcage resonator for EPR irradiation. Experiments to image the distribution of an exogenous nitroxide free radical in anaesthetized rabbits are described.",

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doi = "10.1088/0031-9155/43/7/008",

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AU - Lurie, David J.

AU - Foster, Margaret A.

AU - Yeung, David

AU - Hutchison, James M S

N1 - We thank Mr E Stevenson, Mr P Mullen and Mr J Carney for help in the construction of the screened room. This work was funded by the Medical Research Council and by the University of Aberdeen.

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N2 - The design, construction and use of a large-scale field-cycled proton- electron double-resonance imaging (FC-PEDRI) imager is described. The imager is based on a whole-body sized, vertical field, 59 mT permanent magnet. Field cycling is accomplished by the field compensation method, and uses a secondary, resistive magnet with an internal diameter of 52 cm. The magnetic field can be switched from zero to 59 mT or vice versa in 40 ms. It is used with a double-resonance coil assembly (NMR/EPR) comprising a solenoidal NMR transmit/receive coil and a coaxial, external birdcage resonator for EPR irradiation. Experiments to image the distribution of an exogenous nitroxide free radical in anaesthetized rabbits are described.

AB - The design, construction and use of a large-scale field-cycled proton- electron double-resonance imaging (FC-PEDRI) imager is described. The imager is based on a whole-body sized, vertical field, 59 mT permanent magnet. Field cycling is accomplished by the field compensation method, and uses a secondary, resistive magnet with an internal diameter of 52 cm. The magnetic field can be switched from zero to 59 mT or vice versa in 40 ms. It is used with a double-resonance coil assembly (NMR/EPR) comprising a solenoidal NMR transmit/receive coil and a coaxial, external birdcage resonator for EPR irradiation. Experiments to image the distribution of an exogenous nitroxide free radical in anaesthetized rabbits are described.

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JO - Physics in Medicine and Biology

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Design, construction and use of a large-sample field-cycled PEDRI imager

Abstract

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