Extensive esophageal papillomatosis after chemoradiotherapy for squamous cell carcinoma

Wilson Siu; Graeme I Murray; Alastair McKinlay; Perminder Phull

doi:10.1016/j.gie.2017.12.001

Extensive esophageal papillomatosis after chemoradiotherapy for squamous cell carcinoma

Wilson Siu, Graeme I Murray, Alastair McKinlay, Perminder Phull

Aberdeen Royal Infirmary

Research output: Contribution to journal › Article › peer-review

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Abstract

A 71-year-old woman presented with dysphagia 2 years after undergoing radical chemoradiotherapy for squamous cell carcinoma of the cervical esophagus. Endoscopy revealed a benign esophageal stricture 20 cm from the incisors, with a 1-cm villiform mass below the stricture (A). The esophageal mass increased in size over the next 4 years, completely obstructing the lumen (B) and extending over a length of 12 cm as shown by contrast swallow (C). Examination of multiple sets of biopsy specimens failed to show any evidence of atypia, high-grade dysplasia, or invasive malignancy, but histologic analysis did show multiple polypoid fragments of squamous esophageal mucosa with the appearance of squamous cell papillomatosis (D, H&E orig.

Original language	English
Pages (from-to)	1581-1582
Number of pages	2
Journal	Gastrointestinal Endoscopy
Volume	87
Issue number	6
Early online date	6 Dec 2017
DOIs	https://doi.org/10.1016/j.gie.2017.12.001
Publication status	Published - Jun 2018

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abstract = "A 71-year-old woman presented with dysphagia 2 years after undergoing radical chemoradiotherapy for squamous cell carcinoma of the cervical esophagus. Endoscopy revealed a benign esophageal stricture 20 cm from the incisors, with a 1-cm villiform mass below the stricture (A). The esophageal mass increased in size over the next 4 years, completely obstructing the lumen (B) and extending over a length of 12 cm as shown by contrast swallow (C). Examination of multiple sets of biopsy specimens failed to show any evidence of atypia, high-grade dysplasia, or invasive malignancy, but histologic analysis did show multiple polypoid fragments of squamous esophageal mucosa with the appearance of squamous cell papillomatosis (D, H&E orig.",

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AU - Siu, Wilson

AU - Murray, Graeme I

AU - McKinlay, Alastair

AU - Phull, Perminder

PY - 2018/6

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N2 - A 71-year-old woman presented with dysphagia 2 years after undergoing radical chemoradiotherapy for squamous cell carcinoma of the cervical esophagus. Endoscopy revealed a benign esophageal stricture 20 cm from the incisors, with a 1-cm villiform mass below the stricture (A). The esophageal mass increased in size over the next 4 years, completely obstructing the lumen (B) and extending over a length of 12 cm as shown by contrast swallow (C). Examination of multiple sets of biopsy specimens failed to show any evidence of atypia, high-grade dysplasia, or invasive malignancy, but histologic analysis did show multiple polypoid fragments of squamous esophageal mucosa with the appearance of squamous cell papillomatosis (D, H&E orig.

AB - A 71-year-old woman presented with dysphagia 2 years after undergoing radical chemoradiotherapy for squamous cell carcinoma of the cervical esophagus. Endoscopy revealed a benign esophageal stricture 20 cm from the incisors, with a 1-cm villiform mass below the stricture (A). The esophageal mass increased in size over the next 4 years, completely obstructing the lumen (B) and extending over a length of 12 cm as shown by contrast swallow (C). Examination of multiple sets of biopsy specimens failed to show any evidence of atypia, high-grade dysplasia, or invasive malignancy, but histologic analysis did show multiple polypoid fragments of squamous esophageal mucosa with the appearance of squamous cell papillomatosis (D, H&E orig.

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DO - 10.1016/j.gie.2017.12.001

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EP - 1582

JO - Gastrointestinal Endoscopy

JF - Gastrointestinal Endoscopy

IS - 6

ER -

Extensive esophageal papillomatosis after chemoradiotherapy for squamous cell carcinoma

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