Fibrinogen depleting agents for acute ischaemic stroke

Zilong Hao, Ming Liu, Carl Counsell, Joanna M Wardlaw, Sen Lin, Xiaoling Zhao

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)


Fibrinogen depleting agents reduce fibrinogen in blood plasma, reduce blood viscosity and hence increase blood flow. This may help remove the blood clot blocking the artery and re-establish blood flow to the affected area of the brain after an ischaemic stroke. The risk of haemorrhage may be less than with thrombolytic agents. This is an update of a Cochrane review first published in 1997 and last updated in 2003.
Original languageEnglish
Article numberCD000091
JournalCochrane Database of Systematic Reviews
Issue number3
Publication statusPublished - 14 Mar 2012


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