Fungal Recognition and Host Defense Mechanisms

I. M. Dambuza, S. M Levitz, M. G. Netea, G. D. Brown

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)
88 Downloads (Pure)

Abstract

Fungi have emerged as premier opportunistic microbes of the 21st century, having a considerable impact on human morbidity and mortality. The huge increase in incidence of these diseases is largely due to the HIV pandemic and use of immunosuppressive therapies, underscoring the importance of the immune system in defense against fungi. This article will address how the mammalian immune system recognizes and mounts a defense against medically relevant fungal species.
Original languageEnglish
Pages (from-to)1-16
Number of pages16
JournalMicrobiology spectrum
Volume5
Issue number4
DOIs
Publication statusPublished - 28 Jul 2017

Bibliographical note

We thank the Wellcome Trust Strategic Award, Wellcome Trust and Medical Research Council Centre for Medical Mycology, and the University of Aberdeen for funding.

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