Gut microbiota: Microbiota organisation-a key to understanding CRC development

Georgina L Hold; Wendy S Garrett

doi:10.1038/nrgastro.2015.25

Gut microbiota: Microbiota organisation-a key to understanding CRC development

Georgina L Hold
, Wendy S Garrett

Applied Medicine

Harvard School of Public Health, Boston, Massachusetts, USA

Research output: Contribution to journal › Article

34 Citations (Scopus)

Abstract

The gut microbiota has an important role in colorectal cancer (CRC). Dejea and colleagues have demonstrated that particular bacterial biofilms are associated with proximal CRC, correlating with changes in tissue biology associated with oncogenesis. These findings provide a fresh perspective on the microbiota in cancer: microbial organization might provide critical insight into understanding CRC development.

Original language	English
Pages (from-to)	128-129
Number of pages	2
Journal	Nature Reviews Gastroenterology & Hepatology
Volume	12
Issue number	3
Early online date	17 Feb 2015
DOIs	https://doi.org/10.1038/nrgastro.2015.25
Publication status	Published - Mar 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

colorectal cancer
microbiome
microbiota

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10.1038/nrgastro.2015.25Licence: Unspecified

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title = "Gut microbiota: Microbiota organisation-a key to understanding CRC development",

abstract = "The gut microbiota has an important role in colorectal cancer (CRC). Dejea and colleagues have demonstrated that particular bacterial biofilms are associated with proximal CRC, correlating with changes in tissue biology associated with oncogenesis. These findings provide a fresh perspective on the microbiota in cancer: microbial organization might provide critical insight into understanding CRC development.",

keywords = "colorectal cancer, microbiome, microbiota",

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AU - Garrett, Wendy S

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AB - The gut microbiota has an important role in colorectal cancer (CRC). Dejea and colleagues have demonstrated that particular bacterial biofilms are associated with proximal CRC, correlating with changes in tissue biology associated with oncogenesis. These findings provide a fresh perspective on the microbiota in cancer: microbial organization might provide critical insight into understanding CRC development.

KW - colorectal cancer

KW - microbiome

KW - microbiota

U2 - 10.1038/nrgastro.2015.25

DO - 10.1038/nrgastro.2015.25

M3 - Article

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JO - Nature Reviews Gastroenterology & Hepatology

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IS - 3

ER -

Gut microbiota: Microbiota organisation-a key to understanding CRC development

Abstract

UN SDGs

Keywords

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