Human Exposure to Hantaviruses Associated with Rodents of the Murinae Subfamily, Madagascar

Harinirina Aina Rabemananjara; Vololoniaina Raharinosy; Ravo Michèle Razafimahefa; Jean Pierre Ravalohery; Jean Théophile Rafisandratantsoa; Soa Fy Andriamandimby; Minoarisoa Rajerison; Soanandrasana Rahelinirina; Aina Harimanana; Judickaelle Irinantenaina; Marie Marie Olive; Christophe Rogier; Noël Tordo; Rainer G. Ulrich; Jean Marc Reynes; Stéphane Petres; Jean Michel Heraud; Sandra Telfer; Claudia Filippone

doi:10.3201/eid2603.190320

Human Exposure to Hantaviruses Associated with Rodents of the Murinae Subfamily, Madagascar

Harinirina Aina Rabemananjara
, Vololoniaina Raharinosy
, Ravo Michèle Razafimahefa
, Jean Pierre Ravalohery
, Jean Théophile Rafisandratantsoa
, Soa Fy Andriamandimby
, Minoarisoa Rajerison
, Soanandrasana Rahelinirina
, Aina Harimanana
, Judickaelle Irinantenaina
, Marie Marie Olive
, Christophe Rogier
, Noël Tordo
, Rainer G. Ulrich
, Jean Marc Reynes
, Stéphane Petres
, Jean Michel Heraud
, Sandra Telfer^* (Corresponding Author)
, Claudia Filippone^* (Corresponding Author)

^*Corresponding author for this work

Aberdeen Centre For Environmental Sustainability

Institut Pasteur de Madagascar
Central Directorate of the French Military Health Service
Institut Pasteur
Institut Pasteur Paris
Federal Research Institute for Animal Health
German Center for Infection Research (DZIF)

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

15 Downloads (Pure)

Abstract

We conducted a national human serologic study of a hantavirus detected in Madagascar rodents using a commercial kit and a new ELISA targeting the virus. Our results suggest a conservative estimate of 2.7% (46/1,680) IgG seroprevalence. A second single-district study using the new ELISA revealed a higher prevalence (7.2%; 10/139).

Original language	English
Pages (from-to)	587-590
Number of pages	4
Journal	Emerging Infectious Diseases
Volume	26
Issue number	3
Early online date	19 Feb 2020
DOIs	https://doi.org/10.3201/eid2603.190320
Publication status	Published - Mar 2020

Bibliographical note

We thank all colleagues from the Virology, Plague and
Epidemiology Units of the Institut Pasteur de Madagascar
who aided with field and laboratory work. We thank
Corinne Jallet for help with some ELISA assays and Rasa
Petraityte-Burneikiene and Aurelija Zvirbliene for providing
antigen for additional analysis. We thank Reagena for
constructive exchanges during provision of the kits.
This work was supported by Wellcome Trust Fellowships
(no. 081705 and 095171 to S.T.) and Institut Pasteur de
Madagascar, and by PTR (Progamme Transversal de
Recherche) HANTAREV at Institut Pasteur, Paris.

Funding

This work was supported by Wellcome Trust Fellowships (no. 081705 and 095171 to S.T.) and Institut Pasteur de Madagascar, and by PTR (Progamme Transversal de Recherche) HANTAREV at Institut Pasteur, Paris.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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Final published version, 565 KBLicence: CC BY

Cite this

Rabemananjara, H. A., Raharinosy, V., Razafimahefa, R. M., Ravalohery, J. P., Rafisandratantsoa, J. T., Andriamandimby, S. F., Rajerison, M., Rahelinirina, S., Harimanana, A., Irinantenaina, J., Olive, M. M., Rogier, C., Tordo, N., Ulrich, R. G., Reynes, J. M., Petres, S., Heraud, J. M., Telfer, S., & Filippone, C. (2020). Human Exposure to Hantaviruses Associated with Rodents of the Murinae Subfamily, Madagascar. Emerging Infectious Diseases, 26(3), 587-590. https://doi.org/10.3201/eid2603.190320

Rabemananjara, HA, Raharinosy, V, Razafimahefa, RM, Ravalohery, JP, Rafisandratantsoa, JT, Andriamandimby, SF, Rajerison, M, Rahelinirina, S, Harimanana, A, Irinantenaina, J, Olive, MM, Rogier, C, Tordo, N, Ulrich, RG, Reynes, JM, Petres, S, Heraud, JM, Telfer, S & Filippone, C 2020, 'Human Exposure to Hantaviruses Associated with Rodents of the Murinae Subfamily, Madagascar', Emerging Infectious Diseases, vol. 26, no. 3, pp. 587-590. https://doi.org/10.3201/eid2603.190320

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title = "Human Exposure to Hantaviruses Associated with Rodents of the Murinae Subfamily, Madagascar",

abstract = "We conducted a national human serologic study of a hantavirus detected in Madagascar rodents using a commercial kit and a new ELISA targeting the virus. Our results suggest a conservative estimate of 2.7\% (46/1,680) IgG seroprevalence. A second single-district study using the new ELISA revealed a higher prevalence (7.2\%; 10/139).",

author = "Rabemananjara, \{Harinirina Aina\} and Vololoniaina Raharinosy and Razafimahefa, \{Ravo Mich{\`e}le\} and Ravalohery, \{Jean Pierre\} and Rafisandratantsoa, \{Jean Th{\'e}ophile\} and Andriamandimby, \{Soa Fy\} and Minoarisoa Rajerison and Soanandrasana Rahelinirina and Aina Harimanana and Judickaelle Irinantenaina and Olive, \{Marie Marie\} and Christophe Rogier and No{\"e}l Tordo and Ulrich, \{Rainer G.\} and Reynes, \{Jean Marc\} and St{\'e}phane Petres and Heraud, \{Jean Michel\} and Sandra Telfer and Claudia Filippone",

note = "We thank all colleagues from the Virology, Plague and Epidemiology Units of the Institut Pasteur de Madagascar who aided with field and laboratory work. We thank Corinne Jallet for help with some ELISA assays and Rasa Petraityte-Burneikiene and Aurelija Zvirbliene for providing antigen for additional analysis. We thank Reagena for constructive exchanges during provision of the kits. This work was supported by Wellcome Trust Fellowships (no. 081705 and 095171 to S.T.) and Institut Pasteur de Madagascar, and by PTR (Progamme Transversal de Recherche) HANTAREV at Institut Pasteur, Paris.",

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AU - Rabemananjara, Harinirina Aina

AU - Raharinosy, Vololoniaina

AU - Razafimahefa, Ravo Michèle

AU - Ravalohery, Jean Pierre

AU - Rafisandratantsoa, Jean Théophile

AU - Andriamandimby, Soa Fy

AU - Rajerison, Minoarisoa

AU - Rahelinirina, Soanandrasana

AU - Harimanana, Aina

AU - Irinantenaina, Judickaelle

AU - Olive, Marie Marie

AU - Rogier, Christophe

AU - Tordo, Noël

AU - Ulrich, Rainer G.

AU - Reynes, Jean Marc

AU - Petres, Stéphane

AU - Heraud, Jean Michel

AU - Telfer, Sandra

AU - Filippone, Claudia

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PY - 2020/3

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AB - We conducted a national human serologic study of a hantavirus detected in Madagascar rodents using a commercial kit and a new ELISA targeting the virus. Our results suggest a conservative estimate of 2.7% (46/1,680) IgG seroprevalence. A second single-district study using the new ELISA revealed a higher prevalence (7.2%; 10/139).

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Human Exposure to Hantaviruses Associated with Rodents of the Murinae Subfamily, Madagascar

Abstract

Bibliographical note

Funding

UN SDGs

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