Anaerostipes caccae gen. nov., sp. nov., a new saccharolytic, acetate-utilising, butyrate-producing bacterium from human faeces

A. Schwiertz; Georgina Louise Hold; S. H. Duncan; B. Grubel; M. D. Collins; P. A. Lawson; Harry James Flint; M. Blaut

doi:10.1078/0723-2020-00096

Anaerostipes caccae gen. nov., sp. nov., a new saccharolytic, acetate-utilising, butyrate-producing bacterium from human faeces

A. Schwiertz, Georgina Louise Hold, S. H. Duncan, B. Grubel, M. D. Collins, P. A. Lawson, Harry James Flint, M. Blaut

Research output: Contribution to journal › Article › peer-review

126 Citations (Scopus)

Abstract

Two strains of a previously undescribed Eubacterium-like bacterium were isolated from human faeces. The strains are Gram-variable, obligately anaerobic, catalase negative, asporogenous rod-shaped cells which produced acetate, butyrate and lactate as the end products of glucose metabolism. The two isolates displayed 99.9% 16S rRNA gene sequence similarity to each other and treeing analysis demonstrated the faecal isolates are far removed from Eubacterium sensu stricto and that they represent a new subline within the Clostridium coccoides group of organisms. Based on phenotypic and phylogenetic criteria, it is proposed that the two strains from faeces be classified as a new genus and species, Anaerostipes caccae. The type strain of Anaerostipes caccae is NCIMB 13811(T) (= DSM 14662(T)).

Original language	English
Pages (from-to)	46-51
Number of pages	5
Journal	Systematic and Applied Microbiology
Volume	25
Issue number	1
DOIs	https://doi.org/10.1078/0723-2020-00096
Publication status	Published - 2002

Keywords

Anaerostipes caccae
16S rRNA
taxonomy
phylogeny
human faeces
16S ribosomal-RNA
human intestinal-tract
human fecal samples
human gut
chromatography
clostridium
communities
reveals

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title = "Anaerostipes caccae gen. nov., sp. nov., a new saccharolytic, acetate-utilising, butyrate-producing bacterium from human faeces",

abstract = "Two strains of a previously undescribed Eubacterium-like bacterium were isolated from human faeces. The strains are Gram-variable, obligately anaerobic, catalase negative, asporogenous rod-shaped cells which produced acetate, butyrate and lactate as the end products of glucose metabolism. The two isolates displayed 99.9% 16S rRNA gene sequence similarity to each other and treeing analysis demonstrated the faecal isolates are far removed from Eubacterium sensu stricto and that they represent a new subline within the Clostridium coccoides group of organisms. Based on phenotypic and phylogenetic criteria, it is proposed that the two strains from faeces be classified as a new genus and species, Anaerostipes caccae. The type strain of Anaerostipes caccae is NCIMB 13811(T) (= DSM 14662(T)).",

keywords = "Anaerostipes caccae, 16S rRNA, taxonomy, phylogeny, human faeces, 16S ribosomal-RNA, human intestinal-tract, human fecal samples, human gut, chromatography, clostridium, communities, reveals",

author = "A. Schwiertz and Hold, {Georgina Louise} and Duncan, {S. H.} and B. Grubel and Collins, {M. D.} and Lawson, {P. A.} and Flint, {Harry James} and M. Blaut",

year = "2002",

doi = "10.1078/0723-2020-00096",

language = "English",

volume = "25",

pages = "46--51",

journal = "Systematic and Applied Microbiology",

issn = "0723-2020",

publisher = "Urban und Fischer Verlag Jena",

number = "1",

}

TY - JOUR

T1 - Anaerostipes caccae gen. nov., sp. nov., a new saccharolytic, acetate-utilising, butyrate-producing bacterium from human faeces

AU - Schwiertz, A.

AU - Hold, Georgina Louise

AU - Duncan, S. H.

AU - Grubel, B.

AU - Collins, M. D.

AU - Lawson, P. A.

AU - Flint, Harry James

AU - Blaut, M.

PY - 2002

Y1 - 2002

N2 - Two strains of a previously undescribed Eubacterium-like bacterium were isolated from human faeces. The strains are Gram-variable, obligately anaerobic, catalase negative, asporogenous rod-shaped cells which produced acetate, butyrate and lactate as the end products of glucose metabolism. The two isolates displayed 99.9% 16S rRNA gene sequence similarity to each other and treeing analysis demonstrated the faecal isolates are far removed from Eubacterium sensu stricto and that they represent a new subline within the Clostridium coccoides group of organisms. Based on phenotypic and phylogenetic criteria, it is proposed that the two strains from faeces be classified as a new genus and species, Anaerostipes caccae. The type strain of Anaerostipes caccae is NCIMB 13811(T) (= DSM 14662(T)).

AB - Two strains of a previously undescribed Eubacterium-like bacterium were isolated from human faeces. The strains are Gram-variable, obligately anaerobic, catalase negative, asporogenous rod-shaped cells which produced acetate, butyrate and lactate as the end products of glucose metabolism. The two isolates displayed 99.9% 16S rRNA gene sequence similarity to each other and treeing analysis demonstrated the faecal isolates are far removed from Eubacterium sensu stricto and that they represent a new subline within the Clostridium coccoides group of organisms. Based on phenotypic and phylogenetic criteria, it is proposed that the two strains from faeces be classified as a new genus and species, Anaerostipes caccae. The type strain of Anaerostipes caccae is NCIMB 13811(T) (= DSM 14662(T)).

KW - Anaerostipes caccae

KW - 16S rRNA

KW - taxonomy

KW - phylogeny

KW - human faeces

KW - 16S ribosomal-RNA

KW - human intestinal-tract

KW - human fecal samples

KW - human gut

KW - chromatography

KW - clostridium

KW - communities

KW - reveals

U2 - 10.1078/0723-2020-00096

DO - 10.1078/0723-2020-00096

M3 - Article

SN - 0723-2020

VL - 25

SP - 46

EP - 51

JO - Systematic and Applied Microbiology

JF - Systematic and Applied Microbiology

IS - 1

ER -

Anaerostipes caccae gen. nov., sp. nov., a new saccharolytic, acetate-utilising, butyrate-producing bacterium from human faeces

Abstract

Keywords

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