Is cervical length associated with maternal characteristics?

A. J. Van Der Ven*, M. A. Van Os, C. E. Kleinrouweler, C. J.M. De Groot, M. C. Haak, B. W.J. Mol, E. Pajkrt, B. M. Kazemier

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)


Abstract Objective Women with a mid-trimester short cervical length (CL) are at increased risk for preterm delivery. Consequently, CL measurement is a potential screening tool to identify women at risk for preterm birth. Our objective was to assess possible associations between CL and maternal characteristics. Study design A nationwide screening study was performed in which CL was measured during the standard anomaly scan among low risk women with a singleton pregnancy. Data on maternal height, pre-pregnancy weight, ethnicity, parity and gestational age at the time of the CL measurement were collected from January 2010 to December 2012. Univariable and multivariable linear regression analyses were performed to assess the relationship between CL and maternal characteristics. Results We included 5092 women. The mean CL was 44.3 mm. No association was found between CL and maternal height or gestational age of the measurement. Maternal weight was associated with CL (p = 0.007, adjusted R 2 0.03). Separate analysis for BMI did not change these results. Ethnicity, known in 2702 out of 5092 women, was associated with CL (mean CL in Caucasian women 45.0 mm, Asian 43.9 mm, Mediterranean 43.1 mm, and African 41.8 mm, p = 0.003), as well as parity (mean CL multiparous 45.3 mm, nulliparous 43.5 mm, p < 0.0001). Conclusion Shorter mid-trimester cervical length is associated with higher maternal weight, younger maternal age, nulliparity and non-Caucasian ethnicity, but not with maternal height.

Original languageEnglish
Article number8928
Pages (from-to)12-16
Number of pages5
JournalEuropean Journal of Obstetrics and Gynecology and Reproductive Biology
Publication statusPublished - 1 May 2015


  • Cervical length
  • Maternal characteristics
  • Maternal height


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