Is there a rationale for an anesthesiologist's role against cancer recurrence?

P. Forget* (Corresponding Author), P.G. Coulie, M. Retsky, R. Demicheli, J.-P. Machiels, M. De Kock

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


Growth of tumors can accelerate during the peri-operative period. Accordingly, early relapse of cancer occurs in some patients during the first two postoperative years. Temporal and biologic analyses of cancer pathophysiology suggest a link between peri-operative pathophysiological changes and acceleration of tumor growth. Understanding the role of inflammation and its consequences (i.e., immune response, growth factors, dissemination of tumor cells) could lead to define a role of anesthesiologists in reducing cancer recurrence following surgery. We argue for peri-operative pharmacological interventions to reduce cancer relapse, with a focus on non-steroidal anti-inflammatory drugs.
Original languageEnglish
Pages (from-to)15-24
Number of pages10
JournalActa Anaesthesiologica Belgica
Issue number1
Publication statusPublished - Mar 2013

Bibliographical note

The authors would like to acknowledge Karen Retsky for her contribution to the quality of the manuscript.

Financial Support : This work was supported by the Belgian Society of Anesthesia and Resuscitation. This work was also supported by the Fondation Saint-Luc, the Departments of Anesthesiology, and the Commission du Patrimoine of the Université catholique de Louvain, St-Luc Hospital. MR is supported by grant KG 100484 from Komen Foundation for the Cure.


  • inflammation
  • non-steroidal anti-inflammatory drugs
  • postoperative cancer recurrence


Dive into the research topics of 'Is there a rationale for an anesthesiologist's role against cancer recurrence?'. Together they form a unique fingerprint.

Cite this