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Male Breast Cancer: Growing Insights and Continuing Challenges

  • Sahar Iftikhar
  • , Elissa Burr
  • , Amal Freigoun
  • , Theo Nearney
  • , Christelle Q Kanda
  • , Hazel Robinson
  • , Caroline Vermeren
  • , Udana Wickramaratne
  • , Matthew Everest
  • , Luca Foley
  • , Valerie Speirs* (Corresponding Author)
  • *Corresponding author for this work
  • University of Aberdeen

Research output: Contribution to journalArticlepeer-review

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Abstract

Background
Breast cancer (BC) in men accounts for less than 1% of all BC diagnoses worldwide. Despite its low incidence, the number of men being diagnosed is increasing. Historically perceived as a predominantly female disease, BC in men has received comparatively limited attention.

Aim
This review aims to examine how BC manifests in men and explored the impact of stigma and awareness on diagnosis and prognosis.

Methods
A narrative review of current literature was undertaken, including epidemiological studies, clinical research and psychosocial analyses relating to male BC.

Results
Male BC shares several pathological and molecular features with female BC, but notable differences exist in presentation, tumour biology and treatment considerations. Men are more likely to present at a later stage of disease, often due to low awareness and misconception that BC affects only women. Stigma and limited targeted education further contribute to delayed medical consultation.

Discussion
Although understanding of male BC has improved, challenges remain in early detection and awareness. The gendered perception of BC may discourage men from seeking timely medical advice, leading to more advanced disease at diagnosis and potentially poorer outcomes.

Conclusion
Addressing stigma, increasing public and professional education and promoting clinical research inclusive of men are essential to improving timely diagnosis and outcomes.
Original languageEnglish
Article numbere71673
Number of pages7
JournalCancer Medicine
Volume15
Issue number3
Early online date3 Mar 2026
DOIs
Publication statusPublished - Mar 2026

Data Availability Statement

Data sharing not applicable to this article as no datasets were generated or analysed during the current study.

Funding

The authors have nothing to report.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • breast cancer
  • epidemiology
  • men
  • stigma
  • Breast Neoplasms, Male/diagnosis
  • Prognosis
  • Early Detection of Cancer
  • Humans
  • Male
  • Female
  • Social Stigma
  • Health Knowledge, Attitudes, Practice

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