TY - JOUR
T1 - O Brasil perante as novas variantes de SARS-CoV-2
T2 - emergências e desafios em saúde pública
AU - Marquitti, Flavia Maria Darcie
AU - Coutinho, Renato Mendes
AU - Ferreira, Leonardo Souto
AU - Borges, Marcelo Eduardo
AU - Portella, Tatiana Pineda
AU - Silva, Rafael Lopes Paixão da
AU - Canton, Otavio
AU - Poloni, Silas
AU - Franco, Caroline
AU - Coelho, Verônica
AU - Barberia, Lorena
AU - Bolle, Monica de
AU - Boing, Alexandra Crispim
AU - Donalisio, Maria Rita
AU - Boing, Antonio Fernando
AU - Silva, Antônio Augusto Moura da
AU - Prado, Paulo Inácio
AU - Veras, Maria Amélia de Sousa Mascena
AU - Kraenkel, Roberto André
PY - 2021/6/7
Y1 - 2021/6/7
N2 - This article discusses the epidemic situation of Covid-19 in Brazil, in the face of the emergence of a new strain called P.1, which is more transmissible and may be associated with reinfection. Given the collapse of hospital care in Manaus in January 2021 and the results of three recent preprints, each that reports increased transmissibility of the P.1 variant, we propose some urgent measures. Genomic surveillance based on multi-step diagnostics, starting with RT-PCR type tests and up to sequencing, should be established. Efforts to identify reinfections associated with this variant and the update of its definition in protocols should be prioritized, and studies on the efficacy of currently available vaccines in Brazil concerning the new variant should be conducted. We also propose improving the Brazilian health surveillance system such that genomic surveillance is coordinated and thereby better able to respond to future emergencies in a more timely fashion. We call on the public agents involved in health surveillance to share data and information regarding the epidemic in a clear, fast and transparent way. Finally, we propose a greater engagement in inter-institutional cooperation of all those involved in the response and production of knowledge about the pandemic in our country.
AB - This article discusses the epidemic situation of Covid-19 in Brazil, in the face of the emergence of a new strain called P.1, which is more transmissible and may be associated with reinfection. Given the collapse of hospital care in Manaus in January 2021 and the results of three recent preprints, each that reports increased transmissibility of the P.1 variant, we propose some urgent measures. Genomic surveillance based on multi-step diagnostics, starting with RT-PCR type tests and up to sequencing, should be established. Efforts to identify reinfections associated with this variant and the update of its definition in protocols should be prioritized, and studies on the efficacy of currently available vaccines in Brazil concerning the new variant should be conducted. We also propose improving the Brazilian health surveillance system such that genomic surveillance is coordinated and thereby better able to respond to future emergencies in a more timely fashion. We call on the public agents involved in health surveillance to share data and information regarding the epidemic in a clear, fast and transparent way. Finally, we propose a greater engagement in inter-institutional cooperation of all those involved in the response and production of knowledge about the pandemic in our country.
KW - coronavirus infections
KW - Surveillance
KW - epidemics
U2 - 10.1590/1980-549720210022
DO - 10.1590/1980-549720210022
M3 - Article
VL - 24
JO - Revista Brasileira de Epidemiologia
JF - Revista Brasileira de Epidemiologia
M1 - E10022
ER -