Optimal gastric pouch reconstruction post-gastrectomy

Shayanthan Nanthakumaran, Stuart A. Suttie, Howard W. Chandler, Kenneth G. M. Park

Research output: Contribution to journalArticle

3 Citations (Scopus)


Background. Gastric pouches have the potential to improve nutrition following total gastrectomy, compared with standard reconstruction. However, a consensus view of clinical benefit is not available, at least partly due to a lack of standardization of pouch design or size. This study was undertaken to identify optimal conditions for pouch design.

Methods. A mathematical model was established and a porcine model constructed to evaluate the pressure/volume dynamics of the pouch. A "J" pouch was constructed at anastomotic lengths of 5, 10, 15, and 20 cm. Each pouch was distended with saline and the pressure/volume relationship established.

Results. Mathematically, increasing the anastomotic length of the pouch to 15 cm increases the volume significantly; thereafter, there is minimal benefit of increasing the pouch length further. For smaller pouches (5 and 10 cm) a 350-to 400-ml volume (approximate meal volume in the elderly) is never achieved until higher pressures (45 cmH(2)O) are applied. However, in the larger pouches (15 and 20 cm) a 350-to 400-ml volume is readily achieved at basal pressures of 15 cmH(2)O.

Conclusion. Smaller pouches never achieve adequate volumes at basal pressures; accordingly, it is unlikely that they will lead to any clinical benefit. Further in-vivo studies should therefore be based upon 15-cm pouch designs.

Original languageEnglish
Pages (from-to)33-36
Number of pages4
JournalGastric Cancer
Issue number1
Publication statusPublished - Mar 2008


  • gastric cancer
  • total gastrectomy
  • gastric pouch
  • reconstruction
  • mathematical modeling
  • quality-of-life
  • jejunal pouch
  • food-intake
  • follow-up
  • consequences
  • construction
  • reservoir
  • cancer


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