Oxide-supported metal catalysts for anaerobic NAD+ regeneration with concurrent hydrogen production

Jianwei Li; Joseph W.H. Burnett; Claudia Martinez Macias; Russell F. Howe; Xiaodong Wang

doi:10.1016/j.cclet.2023.108737

Oxide-supported metal catalysts for anaerobic NAD⁺ regeneration with concurrent hydrogen production

Jianwei Li
, Joseph W.H. Burnett
, Claudia Martinez Macias
, Russell F. Howe
, Xiaodong Wang^*

^*Corresponding author for this work

Lancaster University

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We report SiO₂-supported monometallic Pt, Pd, Au, Ni, Cu and Co catalysts for proton-driven NAD⁺ regeneration, co-producing H₂. All metals are fully selective to NAD⁺ where the order of turnover frequencies (Pt > Pd > Cu > Au, Ni and Co) coincides with those otherwise observed in electrochemical hydrogen evolution reactions. This has revealed that NADH is capable of converting the metal sites into a “cathode” without an external potential and the NADH to NAD⁺ reaction involves transferring electron and hydrogen atom separately. Electron-deficient Pt^δ⁺ (on CeO₂) enhances TOF and the heterogeneous Pt/CeO₂ catalyst is recyclable without losing any activity/selectivity.

Original language	English
Article number	108737
Journal	Chinese Chemical Letters
Volume	35
Issue number	2
DOIs	https://doi.org/10.1016/j.cclet.2023.108737
Publication status	Published - Feb 2024

Funding

This work was supported by the EPSRC New Horizons grants (Nos. EP/V048635/1 and EP/X018172/1). We are also grateful for support from the UK Catalysis Hub funded by EPSRC grant reference EP/R026645/1.

Funders	Funder number
Engineering and Physical Sciences Research Council	EP/R026645/1, EP/V048635/1, EP/X018172/1

Keywords

Heterogeneous catalyst
Hydrogen binding energy
Hydrogen production
Hydrogenase mimic
NAD regeneration

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

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title = "Oxide-supported metal catalysts for anaerobic NAD+ regeneration with concurrent hydrogen production",

abstract = "We report SiO2-supported monometallic Pt, Pd, Au, Ni, Cu and Co catalysts for proton-driven NAD+ regeneration, co-producing H2. All metals are fully selective to NAD+ where the order of turnover frequencies (Pt > Pd > Cu > Au, Ni and Co) coincides with those otherwise observed in electrochemical hydrogen evolution reactions. This has revealed that NADH is capable of converting the metal sites into a “cathode” without an external potential and the NADH to NAD+ reaction involves transferring electron and hydrogen atom separately. Electron-deficient Ptδ+ (on CeO2) enhances TOF and the heterogeneous Pt/CeO2 catalyst is recyclable without losing any activity/selectivity.",

keywords = "Heterogeneous catalyst, Hydrogen binding energy, Hydrogen production, Hydrogenase mimic, NAD regeneration",

author = "Jianwei Li and Burnett, \{Joseph W.H.\} and Macias, \{Claudia Martinez\} and Howe, \{Russell F.\} and Xiaodong Wang",

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T1 - Oxide-supported metal catalysts for anaerobic NAD+ regeneration with concurrent hydrogen production

AU - Li, Jianwei

AU - Burnett, Joseph W.H.

AU - Macias, Claudia Martinez

AU - Howe, Russell F.

AU - Wang, Xiaodong

PY - 2024/2

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N2 - We report SiO2-supported monometallic Pt, Pd, Au, Ni, Cu and Co catalysts for proton-driven NAD+ regeneration, co-producing H2. All metals are fully selective to NAD+ where the order of turnover frequencies (Pt > Pd > Cu > Au, Ni and Co) coincides with those otherwise observed in electrochemical hydrogen evolution reactions. This has revealed that NADH is capable of converting the metal sites into a “cathode” without an external potential and the NADH to NAD+ reaction involves transferring electron and hydrogen atom separately. Electron-deficient Ptδ+ (on CeO2) enhances TOF and the heterogeneous Pt/CeO2 catalyst is recyclable without losing any activity/selectivity.

AB - We report SiO2-supported monometallic Pt, Pd, Au, Ni, Cu and Co catalysts for proton-driven NAD+ regeneration, co-producing H2. All metals are fully selective to NAD+ where the order of turnover frequencies (Pt > Pd > Cu > Au, Ni and Co) coincides with those otherwise observed in electrochemical hydrogen evolution reactions. This has revealed that NADH is capable of converting the metal sites into a “cathode” without an external potential and the NADH to NAD+ reaction involves transferring electron and hydrogen atom separately. Electron-deficient Ptδ+ (on CeO2) enhances TOF and the heterogeneous Pt/CeO2 catalyst is recyclable without losing any activity/selectivity.

KW - Heterogeneous catalyst

KW - Hydrogen binding energy

KW - Hydrogen production

KW - Hydrogenase mimic

KW - NAD regeneration

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DO - 10.1016/j.cclet.2023.108737

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