Perinatal death beyond 41 weeks pregnancy: An evaluation of causes and substandard care factors as identified in perinatal audit in the Netherlands

Joep C. Kortekaas* (Corresponding Author), Anke C. Scheuer, Esteriek De Miranda, Aimée E. Van Dijk, Judit K.J. Keulen, Aafke Bruinsma, Ben W.J. Mol, Frank P.H.A. Vandenbussche, Jeroen Van Dillen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)
4 Downloads (Pure)


Background: Late- and postterm pregnancy are associated with adverse perinatal outcomes, like perinatal death. We evaluated causes of death and substandard care factors (SSFs) in term and postterm perinatal death. Methods: We used data from the Perinatal Audit Registry of the Netherlands (PARS). Women with a term perinatal death registered in PARS were stratified by gestational age into early-/full-term (37.0-40.6) and late-/postterm (≥41.0 weeks) death. Cause of death and SSFs ≥41 weeks were scored and classified by the local perinatal audit teams. Results: During 2010-2012, 947/479,097 (0.21%) term deaths occurred, from which 707 cases (75%) were registered and could be used for analyses. Five hundred ninety-eight early-/full-term and 109 late-/postterm audited deaths were registered in the PARS database. Of all audited cases of perinatal death in the PARS database, 55.2% in the early-/fullterm group occurred antepartum compared to 42.2% in the late-/postterm group, while intrapartum death occurred in 7.2% in the early-/full-term group compared to 19.3% in the late-/postterm group in the audited cases from the PARS database. According to the local perinatal audit, the most relevant causes of perinatal death ≥41 weeks were antepartum asphyxia (7.3%), intrapartum asphyxia (9.2%), neonatal asphyxia (10.1%) and placental insufficiency (10.1%). In the group with perinatal death ≥41 weeks there was ≥1SSF identified in 68.8%. The most frequent SSFs concerned inadequate cardiotocography (CTG) evaluation and/or classification (10.1%), incomplete registration or documentation in medical files (4.6%) or inadequate action on decreased foetal movements (4.6%). Conclusions: In the Netherlands Perinatal Audit Registry, stillbirth occurred relatively less often antepartum and more often intrapartum in pregnancies ≥41 weeks compared to pregnancies at 37.0-40.6 weeks in the audited cases from the PARS database. Foetal, intrapartum and neonatal asphyxia were identified more frequently as cause of death in pregnancies ≥41 weeks. The most identified SSFs related to death in pregnancies ≥41 weeks concerned inadequate CTG monitoring (evaluation, classification, registration or documentation) and inadequate action on decreased foetal movements.

Original languageEnglish
Article number380
Pages (from-to)1-9
Number of pages9
JournalBMC Pregnancy and Childbirth
Early online date20 Sept 2018
Publication statusPublished - 20 Sept 2018

Data Availability Statement

All authors had full access to the data and materials. The data that support the findings of this study are available from Perined but restrictions apply to the availability of these data, which were used under license for the current
study, and so are not publicly available. Data are however available from the authors upon reasonable request and with permission of Perined.


  • CTG
  • Delivery
  • Foetal monitoring
  • Late-term pregnancy
  • Mortality
  • Postterm pregnancy
  • Pregnancy
  • Stillbirth


Dive into the research topics of 'Perinatal death beyond 41 weeks pregnancy: An evaluation of causes and substandard care factors as identified in perinatal audit in the Netherlands'. Together they form a unique fingerprint.

Cite this