Pharmacokinetic assessment of novel anti-cancer drugs using spectral analysis and positron emission tomography: a feasibility study

S R Meikle; J C Matthews; C S Brock; P Wells; R J Harte; V J Cunningham; T Jones; P Price

Pharmacokinetic assessment of novel anti-cancer drugs using spectral analysis and positron emission tomography: a feasibility study

S R Meikle
, J C Matthews
, C S Brock
, P Wells
, R J Harte
, V J Cunningham
, T Jones
, P Price

Research output: Contribution to journal › Article › peer-review

Abstract

The aim of this study was to investigate the feasibility of evaluating the pharmacokinetics of radiolabeled anti-cancer drugs using spectral analysis, a non-compartmental tracer kinetic modeling technique, and positron emission tomography (PET).

Original language	English
Pages (from-to)	183-93
Number of pages	11
Journal	Cancer Chemotherapy and Pharmacology
Volume	42
Issue number	3
Publication status	Published - 1998

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Acridines
Antimetabolites, Antineoplastic
Antineoplastic Agents, Alkylating
Colorectal Neoplasms
Dacarbazine
Feasibility Studies
Female
Fluorouracil
Glioma
Humans
Middle Aged
Spectrum Analysis
Tomography, Emission-Computed

Cite this

@article{c59e39b9bb914264b7dd6d5ed1a83032,

title = "Pharmacokinetic assessment of novel anti-cancer drugs using spectral analysis and positron emission tomography: a feasibility study",

abstract = "The aim of this study was to investigate the feasibility of evaluating the pharmacokinetics of radiolabeled anti-cancer drugs using spectral analysis, a non-compartmental tracer kinetic modeling technique, and positron emission tomography (PET).",

keywords = "Acridines, Antimetabolites, Antineoplastic, Antineoplastic Agents, Alkylating, Colorectal Neoplasms, Dacarbazine, Feasibility Studies, Female, Fluorouracil, Glioma, Humans, Middle Aged, Spectrum Analysis, Tomography, Emission-Computed",

author = "Meikle, \{S R\} and Matthews, \{J C\} and Brock, \{C S\} and P Wells and Harte, \{R J\} and Cunningham, \{V J\} and T Jones and P Price",

year = "1998",

language = "English",

volume = "42",

pages = "183--93",

journal = "Cancer Chemotherapy and Pharmacology",

issn = "0344-5704",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "3",

}

TY - JOUR

T1 - Pharmacokinetic assessment of novel anti-cancer drugs using spectral analysis and positron emission tomography: a feasibility study

AU - Meikle, S R

AU - Matthews, J C

AU - Brock, C S

AU - Wells, P

AU - Harte, R J

AU - Cunningham, V J

AU - Jones, T

AU - Price, P

PY - 1998

Y1 - 1998

N2 - The aim of this study was to investigate the feasibility of evaluating the pharmacokinetics of radiolabeled anti-cancer drugs using spectral analysis, a non-compartmental tracer kinetic modeling technique, and positron emission tomography (PET).

AB - The aim of this study was to investigate the feasibility of evaluating the pharmacokinetics of radiolabeled anti-cancer drugs using spectral analysis, a non-compartmental tracer kinetic modeling technique, and positron emission tomography (PET).

KW - Acridines

KW - Antimetabolites, Antineoplastic

KW - Antineoplastic Agents, Alkylating

KW - Colorectal Neoplasms

KW - Dacarbazine

KW - Feasibility Studies

KW - Female

KW - Fluorouracil

KW - Glioma

KW - Humans

KW - Middle Aged

KW - Spectrum Analysis

KW - Tomography, Emission-Computed

M3 - Article

C2 - 9685053

SN - 0344-5704

VL - 42

SP - 183

EP - 193

JO - Cancer Chemotherapy and Pharmacology

JF - Cancer Chemotherapy and Pharmacology

IS - 3

ER -

Pharmacokinetic assessment of novel anti-cancer drugs using spectral analysis and positron emission tomography: a feasibility study

Abstract

UN SDGs

Keywords

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