Abstract
The concept of pre-diabetes has led to provision of measures to reduce disease progression through identification of subjects at risk of diabetes. We previously considered the idea of pre-asthma in relation to allergic asthma and considered that, in addition to the need to improve population health via multiple measures, including reduction of exposure to allergens and pollutants and avoidance of obesity, there are several possible specific means to reduce asthma development in those most at risk (pre- asthma). The most obvious is allergen immunotherapy (AIT), which when given for allergic rhinitis (AR) has reasonable evidence to support asthma prevention in children (2) but also needs further study as primary prevention. In this second paper we explore the possibilities for similar actions in late onset eosinophilic asthma.
| Original language | English |
|---|---|
| Article number | 1404735 |
| Number of pages | 12 |
| Journal | Frontiers in Allergy |
| Volume | 5 |
| Early online date | 15 May 2024 |
| DOIs | |
| Publication status | Published - 15 May 2024 |
Data Availability Statement
All relevant data is contained within the article: The original contributions presented in the study are included in the article, further inquiries can be directed to the corresponding author.Keywords
- chronic rhinosinusitis with nasal polyps
- eosinophils
- late onset asthma
- mast cells
- non-allergic rhinitis
- S. aureus biofilm
- virulence genes
Access to Document
- Scadding_etal_FiA_Pre-asthma_A_Useful_VoR
© 2024 Scadding, Gray, Conti, McDonald, Backer, Scadding, Bernal-Sprekelsen, De Corso, Diamant, Hopkins, Jesenak, Johansen, Kappen, Mullol, Price, Quirce, Reitsma, Toppila-Salmi, Senior, Thyssen, Wahn and Hellings. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). https://creativecommons.org/licenses/by/4.0/