Preventie van vroeggeboorte met progestativa

Translated title of the contribution: Prevention of preterm delivery with progesterones

K. K. Janssen*, B. W. Mol, K. Boer, H. W. Bruinse

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


All treatment modalities aimed at prevention of a spontaneous preterm delivery - with the exception of a prophylactic cerclage in case of an evident insufficiency of the cervix - were till recently ineffective. However, prophylactic administration of progesterone by weekly injections or by daily vaginal administration from the 16th week of gestation onwards reduced significantly the incidence of spontaneous preterm delivery in pregnancies at high risk for preterm delivery as recently described in two randomised studies. After a spontaneous preterm delivery couples need to be informed about this prophylactic treatment in a next pregnancy.

Translated title of the contributionPrevention of preterm delivery with progesterones
Original languageDutch
Pages (from-to)145-147
Number of pages3
JournalTijdschrift voor Kindergeneeskunde
Issue number4
Publication statusPublished - 1 Aug 2005


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