Protozoal sequences may reveal additional isoforms of the 14-3-3 protein family

N. R. McEwan, S. C. Eschenlauer, R. E. Calza, R. J. Wallace, C. J. Newbold

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


The phylogenetic position of eleven 14-3-3 proteins from five protozoal species was tested relative to other eukaryotic 14-3-3 versions representing many of the previously described isoforms. The protozoal proteins, four from Entodinium caudatum, three from Entameoba histolytica and four from apicomplexan parasites formed clusters closer to the plant and animal epsilon isoforms than to the animal beta, gamma/eta, sigma/theta, and zeta isoforms. This extends the preliminary findings of Wang and Shakes (1996) but data from a wider range of genera are still required to strengthen our hypothesis that the protozoan isoforms may constitute novel isoforms of the 14-3-3 family
Original languageEnglish
Pages (from-to)257-264
Number of pages8
Issue number3
Publication statusPublished - Oct 1999

Bibliographical note

UI - 20042953 LA - Eng RN - 0 (Proteins) RN - 0 (Protozoan Proteins) RN - 0 (14-3-3 protein) PT - JOURNAL ARTICLE DA - 19991221 IS - 1434-4610 SB - M CY - GERMANY JC - DGX AA - Author EM - 200002


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