Raman microscopy of bone

Simon R. Goodyear, Richard M. Aspden

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Raman microscopy is a non-destructive technique requiring minimal sample preparation that can be used to measure the chemical properties of the mineral and collagen parts of bone simultaneously. Modern Raman instruments contain the necessary components and software to acquire the standard information required in most bone studies. The spatial resolution of the technique is about a micron. As it is non-destructive and small samples can be used, it forms a useful part of a bone characterisation toolbox.
Original languageEnglish
Pages (from-to)527-534
Number of pages8
JournalMethods in Molecular Biology
Publication statusPublished - 2012


  • Raman spectroscopy
  • bone chemistry
  • composition


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