Receptor conformational change induces fluoride binding despite competitive water binding

Laurent Trembleau; Tim A. D. Smith; Mostafa H Abdelrahman

doi:10.1039/c3cc43019g

Receptor conformational change induces fluoride binding despite competitive water binding

Laurent Trembleau^* (Corresponding Author)
, Tim A. D. Smith
, Mostafa H Abdelrahman

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

Fluoride binding by artificial receptors in water remains a challenging task due to the high hydration enthalpy of this anion. A novel cationic boron-based tripodal receptor featuring three flexible ammonium-containing arms has been prepared. NMR spectroscopy studies show that the receptor is capable of binding selectively the fluoride anion with high affinity in acidic water.

Original language	English
Pages (from-to)	5850-5852
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	52
Early online date	9 May 2013
DOIs	https://doi.org/10.1039/c3cc43019g
Publication status	Published - 4 Jul 2013

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title = "Receptor conformational change induces fluoride binding despite competitive water binding",

abstract = "Fluoride binding by artificial receptors in water remains a challenging task due to the high hydration enthalpy of this anion. A novel cationic boron-based tripodal receptor featuring three flexible ammonium-containing arms has been prepared. NMR spectroscopy studies show that the receptor is capable of binding selectively the fluoride anion with high affinity in acidic water. ",

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AU - Abdelrahman, Mostafa H

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AB - Fluoride binding by artificial receptors in water remains a challenging task due to the high hydration enthalpy of this anion. A novel cationic boron-based tripodal receptor featuring three flexible ammonium-containing arms has been prepared. NMR spectroscopy studies show that the receptor is capable of binding selectively the fluoride anion with high affinity in acidic water.

U2 - 10.1039/c3cc43019g

DO - 10.1039/c3cc43019g

M3 - Article

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JO - Chemical Communications

JF - Chemical Communications

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Receptor conformational change induces fluoride binding despite competitive water binding

Abstract

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