Abstract
Resveratrol, a polyphenolic phytoalexin, is one of the most extensively studied natural products, with wide ranging biological activity and tremendous clinical potential. First identified from fruits and plants, in particular grapes and wines, its positive effects on a variety of disease states have been unraveled over the past decade or so. Most noticeable are its anti-thrombogenic, anti-inflammatory, cardio-protective, neuro-protective, anti-aging, and cancer preventive and therapeutic activities. Recent data also indicate that depending upon the concentration/dose, resveratrol can trigger or block cell death signaling in tumor cells. Considering the heightened interest in this compound, here we present a short review on the biological activity of this remarkable compound, with a specific focus on its effects on cell survival and death signals.
| Original language | English |
|---|---|
| Pages (from-to) | 59-63 |
| Number of pages | 5 |
| Journal | Journal of bioenergetics and biomembranes |
| Volume | 39 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1 Feb 2007 |
Funding
Acknowledgements S.P. is supported by the National Medical Research Council and the Biomedical Research Council, Singapore, as well as the Academic Research Fund, NUS, Singapore. A.L.H is supported by the Academic Research Fund, NUS, Singapore.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Apoptosis
- Mitochondria
- Resveratrol
- ROS
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