Size matters

Li Su; Hai Deng

doi:10.1038/s41589-023-01503-2

Size matters

Li Su
, Hai Deng^* (Corresponding Author)

^*Corresponding author for this work

Chemistry

Max Planck Institute for Terrestrial Microbiology

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Cyclic tetrapeptides (CTPs) have great potential for materials and therapeutics; however, synthesizing these molecules remains a significant challenge. Now, an enzyme has been developed that enables efficient N-to-C cyclization of linear tetrapeptidyl substrates to form structurally diverse CTPs.

Original language	English
Pages (from-to)	8-10
Number of pages	3
Journal	Nature Chemical Biology
Volume	20
DOIs	https://doi.org/10.1038/s41589-023-01503-2
Publication status	Published - Jan 2024

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title = "Size matters",

abstract = "Cyclic tetrapeptides (CTPs) have great potential for materials and therapeutics; however, synthesizing these molecules remains a significant challenge. Now, an enzyme has been developed that enables efficient N-to-C cyclization of linear tetrapeptidyl substrates to form structurally diverse CTPs.",

author = "Li Su and Hai Deng",

year = "2024",

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doi = "10.1038/s41589-023-01503-2",

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AB - Cyclic tetrapeptides (CTPs) have great potential for materials and therapeutics; however, synthesizing these molecules remains a significant challenge. Now, an enzyme has been developed that enables efficient N-to-C cyclization of linear tetrapeptidyl substrates to form structurally diverse CTPs.

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DO - 10.1038/s41589-023-01503-2

M3 - Comment/debate

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SN - 1552-4450

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JO - Nature Chemical Biology

JF - Nature Chemical Biology

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Size matters

Abstract

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