SWATted away: the challenging experience of setting up a programme of SWATs in paediatric trials

Jacqueline Martin-Kerry (Corresponding Author), Adwoa Parker, Peter Bower, Ian Watt, Shaun Treweek, David Torgerson, Catherine Arundel, Peter Knapp

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)
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Randomised controlled trials are considered the best method for determining the effectiveness and safety of health interventions. Trials involving children are essential to ensure that treatments are safe and effective. However, many trials, in both adult and paediatric populations, do not achieve recruitment targets and/or maintain retention of participants, which can lead to a reduction in the internal and external validity of the results. Identifying ways of improving trial efficiency are important in order to increase the successful completion of trials.
Original languageEnglish
Article number141
Issue number1
Publication statusPublished - 19 Feb 2019

Bibliographical note

The authors wish to acknowledge the National Institute of Health Research (NIHR) Health Services and Delivery Research funding for the TRECA study (NIHR Health Services and Delivery Research Project: 14/21/21). The NIHR did not have a role in the design of the study or the writing of this manuscript. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health.


  • ‘SStudy Within A Trial’ (SWAT)
  • embedded trials
  • methodology
  • challenges
  • randomised controlled trials
  • paediatrics
  • governance
  • 'SStudy Within A Trial' (SWAT)


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