Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives

Jun Cheng; Jiangtao Xie; Xianjin Luo

doi:10.1016/j.bmcl.2004.10.087

Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives

Jun Cheng, Jiangtao Xie, Xianjin Luo

Chemistry

Research output: Contribution to journal › Article › peer-review

116 Citations (Scopus)

Abstract

Some benzimidazole derivatives were synthesized and evaluated for their antiviral properties. Compounds 20 and 21 showed potent selective activity against Coxsackie virus B-3 in VERO cells. Some structure-activity relationships were discussed. (C) 2004 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	267-269
Number of pages	3
Journal	Bioorganic & Medicinal Chemistry Letters
Volume	15
Issue number	2
Early online date	24 Nov 2004
DOIs	https://doi.org/10.1016/j.bmcl.2004.10.087
Publication status	Published - 17 Jan 2005

Keywords

benzimidazole
Coxsackie virus B3
antiviral

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10.1016/j.bmcl.2004.10.087

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title = "Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives",

abstract = "Some benzimidazole derivatives were synthesized and evaluated for their antiviral properties. Compounds 20 and 21 showed potent selective activity against Coxsackie virus B-3 in VERO cells. Some structure-activity relationships were discussed. (C) 2004 Elsevier Ltd. All rights reserved.",

keywords = "benzimidazole, Coxsackie virus B3, antiviral",

author = "Jun Cheng and Jiangtao Xie and Xianjin Luo",

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doi = "10.1016/j.bmcl.2004.10.087",

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journal = "Bioorganic & Medicinal Chemistry Letters",

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T1 - Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives

AU - Cheng, Jun

AU - Xie, Jiangtao

AU - Luo, Xianjin

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Y1 - 2005/1/17

N2 - Some benzimidazole derivatives were synthesized and evaluated for their antiviral properties. Compounds 20 and 21 showed potent selective activity against Coxsackie virus B-3 in VERO cells. Some structure-activity relationships were discussed. (C) 2004 Elsevier Ltd. All rights reserved.

AB - Some benzimidazole derivatives were synthesized and evaluated for their antiviral properties. Compounds 20 and 21 showed potent selective activity against Coxsackie virus B-3 in VERO cells. Some structure-activity relationships were discussed. (C) 2004 Elsevier Ltd. All rights reserved.

KW - benzimidazole

KW - Coxsackie virus B3

KW - antiviral

U2 - 10.1016/j.bmcl.2004.10.087

DO - 10.1016/j.bmcl.2004.10.087

M3 - Article

SN - 0960-894X

VL - 15

SP - 267

EP - 269

JO - Bioorganic & Medicinal Chemistry Letters

JF - Bioorganic & Medicinal Chemistry Letters

IS - 2

ER -

Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives

Abstract

Keywords

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