Th1/Th2 cytokines in AIDS: sorting out the confusion

Research output: Contribution to journalComment/debatepeer-review


The type I/type 2 cytokine balance concept may help to account, at least in part, for the immunopathogenesis of AIDS. Type 1 cytokines are suggested by Clerici and Shearer (this Forum) to prevent CD4 ÷ cell loss and dysfunction by programmed cell death (PCD) and type 2 cytokines enhance PCD. However, the type 1/type 2 cytokine profile relationship and its involvement in disease progression in HIV-
infected individuals is incompletely understood.
Original languageEnglish
Pages (from-to)715
Number of pages1
JournalResearch in Immunology
Issue number8-9
Publication statusPublished - 1994


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