Thalidomide: the drug with a dark side but an enigmatic future

Research output: Contribution to specialist publicationArticle

Abstract

The drug thalidomide has a notorious past. It was used between 1957-62 as a sedative and to treat morning sickness in early pregnancy but a serious side effect resulted in over 10,000 children born with severe birth defects.

How the drug caused these defects, which could affect most parts of the body and includes phocomelia – where the limbs are shortened and missing the long bones with the digits in some cases extruding from the shoulder or the hip – is becoming clearer.
Original languageEnglish
Specialist publicationThe Conversation
PublisherThe Conversation UK
Publication statusPublished - 10 Dec 2015

Bibliographical note

Neil Vargesson receives or has received funding for thalidomide research from the Wellcome Trust, the Royal Society, University of Aberdeen, Imperial College London.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Cancer
  • India
  • Brazil
  • Thalidomide
  • Crohn's disease
  • Leprosy
  • Thalidomide series

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