Description
Data resulting from studying the potential therapeutic benefits of GLP-1R agonists (here liraglutide) in lipoatrophic diabetes. Here Seipin-deficient Bscl2 null mice, modelling Congenital Generalised Lipodystrophy Type 2 (CGL2) were treated acutely or for 14 days with liraglutide. Assessments of glucose tolerance, insulin tolerance, pyruvate tolerance were made as well as determination of changes to hepatic steatosis, insulin secretion, pancreas histology and appetite regulation.
Data type
Excel data sheets and image files
Dataset version
1.0
| Date made available | 6 Feb 2024 |
|---|---|
| Publisher | University of Aberdeen |
Funder and Grant Reference number
- Other
- Diabetes UK:18/0005884
- Biotechnology and Biological Sciences Research Council (BBSRC)
- BB/V015869/1
