Elizabeth Hay

2022

Targeting the IL-6-Yap-Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis

Symons, R. A., Colella, F., Collins, F. L., Rafipay, A. J., Kania, K., McClure, J. J., White, N., Cunningham, I., Ashraf, S., Hay, E., Mackenzie, K. S., Howard, K. A., Riemen, A. H. K., Manzo, A., Clark, S. M., Roelofs, A. J. & De Bari, C., Feb 2022, In: Annals of the Rheumatic Diseases. 81, 2, p. 214-224 11 p.

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23 Citations (Scopus)

6 Downloads (Pure)

2021

CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

McEwan, A. R., Davidson, C., Hay, E., Turnbull, Y., Erickson, J. C., Marini, P., Wilson, D., McIntosh, A., Adams, M. J., Murgatroyd, C., Barrett, P., Delibegovic, M., Clarke, T-K. & MacKenzie, A., 2021, In: Molecular Psychiatry. 26, p. 2263–2276 14 p.

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5 Citations (Scopus)

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2020

Palmitic acid triggers inflammatory responses in N42 cultured hypothalamic cells partially via ceramide synthesis but not via TLR4

Sergi, D., Morris, A. C., Kahn, D. E., McLean, F. H., Hay, E. A., Kubitz, P., MacKenzie, A., Martinoli, M. G., Drew, J. E. & Williams, L. M., Apr 2020, In: Nutritional Neuroscience. 23, 4, p. 321-334 14 p.

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47 Citations (Scopus)

Disease associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue specific activity of the cannabinoid‐1 receptor gene promoter; implications for cannabinoid pharmacogenetics

Hay, E. A., Cowie, P., McEwan, A. R., Ross, R., Pertwee, R. G. & MacKenzie, A., 1 Jan 2020, In: Human Mutation. 41, 1, p. 291-298 8 p.

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5 Citations (Scopus)

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2019

Early and reversible changes to the hippocampal proteome in mice on a high-fat diet

McLean, F. H., Campbell, F. M., Sergi, D., Grant, C., Morris, A. C., Hay, E. A., MacKenzie, A., Mayer, C-D., Langston, R. F. & Williams, L. M., Dec 2019, In: Nutrition and Metabolism. 16, 1, 12 p., 57.

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22 Citations (Scopus)

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Disruption of an enhancer associated with addictive behaviour within the cannabinoid receptor-1 gene suggests a possible role in alcohol intake, cannabinoid response and anxiety-related behaviour

Hay, E. A., McEwan, A., Wilson, D., Barrett, P., D'Agostino, G., Pertwee, R. G. & MacKenzie, A., Nov 2019, In: Psychoneuroendocrinology. 109, p. 104407 8 p., 104407.

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14 Citations (Scopus)

9 Downloads (Pure)

2017

An analysis of possible off target effects following CAS9/CRISPR targeted deletions of neuropeptide gene enhancers from the mouse genome

Hay, E. A., Khalaf, A. R., Marini, P., Brown, A., Heath, K., Sheppard, D. & MacKenzie, A., Aug 2017, In: Neuropeptides. 64, p. 101-107 7 p.

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22 Citations (Scopus)

12 Downloads (Pure)

Using the CRISPR/Cas9 system to understand neuropeptide biology and regulation

Hay, E. A., Knowles, C., Kolb, A. & MacKenzie, A., Aug 2017, In: Neuropeptides. 64, p. 19-25 7 p.

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4 Citations (Scopus)

12 Downloads (Pure)

A seasonal switch in histone deacetylase gene expression in the hypothalamus and their capacity to modulate nuclear signaling pathways

Stoney, P. N., Rodrigues, D., Helfer, G., Khatib, T., Ashton, A., Hay, E. A., Starr, R., Kociszewska, D., Morgan, P. & McCaffery, P., Mar 2017, In: Brain, Behavior, and Immunity. 61, p. 340-352 13 p.

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