A homologous series of eunicellin-based diterpenes from Acalycigorgia sp. characterised by tandem mass spectrometry

Kwaku Kyeremeh; Thomas Baddeley; B. K. Stein; Marcel Jaspars

doi:10.1016/j.tet.2006.06.102

A homologous series of eunicellin-based diterpenes from Acalycigorgia sp. characterised by tandem mass spectrometry

Kwaku Kyeremeh, Thomas Baddeley, B. K. Stein, Marcel Jaspars

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

The discovery and structure determination of a homologous series of eunicellin-based diterpenes from the gorgonian Acalycigorgia sp. is described. Extensive use was made of ID and 2D NMR data to determine the structure of the diterpene skeleton. The relative stereochemistry was confirmed via the use of NOE data in conjunction with molecular modelling. A series of homologues were identified using a combination of product and precursor ion scanning modes in tandem mass spectrometry. This powerful technique afforded excellent clarification to aid the analysis of the complex mass spectral data. (c) 2006 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	8770-8778
Number of pages	9
Journal	Tetrahedron
Volume	62
DOIs	https://doi.org/10.1016/j.tet.2006.06.102
Publication status	Published - 2006

Keywords

coral litophyton sp
configuration
gorgonians
molecules
agents

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10.1016/j.tet.2006.06.102

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title = "A homologous series of eunicellin-based diterpenes from Acalycigorgia sp. characterised by tandem mass spectrometry",

abstract = "The discovery and structure determination of a homologous series of eunicellin-based diterpenes from the gorgonian Acalycigorgia sp. is described. Extensive use was made of ID and 2D NMR data to determine the structure of the diterpene skeleton. The relative stereochemistry was confirmed via the use of NOE data in conjunction with molecular modelling. A series of homologues were identified using a combination of product and precursor ion scanning modes in tandem mass spectrometry. This powerful technique afforded excellent clarification to aid the analysis of the complex mass spectral data. (c) 2006 Elsevier Ltd. All rights reserved.",

keywords = "coral litophyton sp, configuration, gorgonians, molecules, agents",

author = "Kwaku Kyeremeh and Thomas Baddeley and Stein, {B. K.} and Marcel Jaspars",

year = "2006",

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T1 - A homologous series of eunicellin-based diterpenes from Acalycigorgia sp. characterised by tandem mass spectrometry

AU - Kyeremeh, Kwaku

AU - Baddeley, Thomas

AU - Stein, B. K.

AU - Jaspars, Marcel

PY - 2006

Y1 - 2006

N2 - The discovery and structure determination of a homologous series of eunicellin-based diterpenes from the gorgonian Acalycigorgia sp. is described. Extensive use was made of ID and 2D NMR data to determine the structure of the diterpene skeleton. The relative stereochemistry was confirmed via the use of NOE data in conjunction with molecular modelling. A series of homologues were identified using a combination of product and precursor ion scanning modes in tandem mass spectrometry. This powerful technique afforded excellent clarification to aid the analysis of the complex mass spectral data. (c) 2006 Elsevier Ltd. All rights reserved.

AB - The discovery and structure determination of a homologous series of eunicellin-based diterpenes from the gorgonian Acalycigorgia sp. is described. Extensive use was made of ID and 2D NMR data to determine the structure of the diterpene skeleton. The relative stereochemistry was confirmed via the use of NOE data in conjunction with molecular modelling. A series of homologues were identified using a combination of product and precursor ion scanning modes in tandem mass spectrometry. This powerful technique afforded excellent clarification to aid the analysis of the complex mass spectral data. (c) 2006 Elsevier Ltd. All rights reserved.

KW - coral litophyton sp

KW - configuration

KW - gorgonians

KW - molecules

KW - agents

U2 - 10.1016/j.tet.2006.06.102

DO - 10.1016/j.tet.2006.06.102

M3 - Article

SN - 0040-4020

VL - 62

SP - 8770

EP - 8778

JO - Tetrahedron

JF - Tetrahedron

ER -

A homologous series of eunicellin-based diterpenes from Acalycigorgia sp. characterised by tandem mass spectrometry

Abstract

Keywords

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