A neglected epidemic: fungal infections in HIV/AIDS

Darius Armstrong-James, Graeme Meintjes, Gordon D Brown

Research output: Contribution to journalArticlepeer-review

223 Citations (Scopus)


Invasive fungal infections (IFIs) are a major cause of HIV-related mortality globally. Despite widespread rollout of combined antiretroviral therapy, there are still up to 1 million deaths annually from IFIs, accounting for 50% of all AIDS-related death. A historic failure to focus efforts on the IFIs that kill so many HIV patients has led to fundamental flaws in the management of advanced HIV infection. This review, based on the EMBO AIDS-Related Mycoses Workshop in Cape Town in July 2013, summarizes the current state of the-art in AIDS-related mycoses, and the key action points required to improve outcomes from these devastating infections.

Original languageEnglish
Pages (from-to)120-127
Number of pages8
JournalTrends in Microbiology
Issue number3
Early online date13 Feb 2014
Publication statusPublished - Mar 2014

Bibliographical note

Copyright © 2014 Elsevier Ltd. All rights reserved.

We thank the Welcome Trust for funding. D.A.J. is supported by an MRC Clinician Scientist Fellowship.


  • HIV
  • fungal infection
  • immunity
  • AIDS
  • mycoses


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