Abstract
Of the total women included in the study, 96 women chose to receive misoprostol 600 mug sublingually while 53 women received misoprostol 800 mug vaginally 36-48 h after receiving mifepristone 200 mg. Complete abortion occurred in 93 women (98.9%) in the sublingual and 51 women (96.2%) in the vaginal group (p=0.27). The mean induction-to-abortion interval was 3.2 h (SD=1.4) in the sublingual and 4.1 h (SD=1.5) in the vaginal group (p=0.02). The mean gestation at abortion in weeks was 7.1 (SD=1.0) in the sublingual and 7.7 (SD=1.3) in the vaginal group (p=0.003). Women in the sublingual group experienced more vomiting (p=0.03), diarrhea (p=0.02) and unpleasant taste in their mouth (p=0.0001) while those in the vaginal group experienced more headache (p=0.002). Of women in the sublingual group, 77% were satisfied with the route of misoprostol administration compared to 68% in the vaginal group (p=0.25). These findings now need to be assessed in the context of a randomized controlled trial. (C) 2003 Elsevier Inc. All rights reserved.
Original language | English |
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Pages (from-to) | 335-338 |
Number of pages | 3 |
Journal | Contraception |
Volume | 68 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2003 |
Keywords
- sublingual
- misoprostol
- medical abortion
- mifepristone
- SURGICAL VACUUM ASPIRATION
- ABORTION
- EFFICACY
- ACCEPTABILITY