A randomized clinical study to evaluate the effect of denture adhesive application technique on food particle accumulation under dentures

Mounir Atassi, Kimberly R. Milleman, Gary R. Burnett, Susmita Sanyal, Jeffery L. Milleman

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)
15 Downloads (Pure)


Food ingress under dentures is a common problem that may be reduced by denture adhesive use. The objective of this study was to explore the effect of the mode of application of a denture adhesive on reducing accumulation of food particles under dentures. This was a single‐centre, controlled, single‐blind, randomized, three‐treatment, three‐period, crossover study in participants with complete, removable well‐fitting, well‐made upper/lower dentures. Treatments were: 1) experimental denture adhesive application (test adhesive) applied with a precision applicator as continuous strips; 2) marketed denture adhesive (positive control) applied using a flat ribbon nozzle as dabs; 3) no adhesive. Food‐occlusion testing was performed by assessing peanut particle migration under dentures with denture retention/stability evaluated using the Kapur Index (Olshan modification). Differences were assessed using an ANOVA model. Adhesive oozing and perceptions of the adhesives were assessed by questionnaire. All 83 randomized participants completed the study. There were no significant differences between positive control or test adhesives versus no adhesive, or between test adhesive and positive control, for mass of peanut particles recovered from dentures. Both adhesives had significantly higher retention and stability scores compared with no adhesive (all P < .01). Participants reported significantly higher scores for denture comfort, confidence, satisfaction and movement with both adhesives versus no adhesive (all P < .01). No differences in adhesive ooze were reported between adhesives. No adverse events were reported. In conclusion, there was no difference in performance, as measured by peanut particle mass recovered from upper/lower dentures, for the test adhesive, positive control and no adhesive.
Original languageEnglish
Pages (from-to)316-325
Number of pages10
JournalClinical and Experimental Dental Research
Issue number4
Early online date17 Jun 2019
Publication statusPublished - Aug 2019

Bibliographical note

Editorial assistance was provided by Julie Adkins of Anthemis Consulting Ltd and Eleanor Roberts of Beeline Science Communications Ltd, both funded by GSK Consumer Healthcare, Weybridge, UK, in accordance with Good Publication Practice (GPP3) guidelines.


  • denture adhesive
  • food-occlusion model
  • retention
  • stability


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