Abstract
Through translational research, the outcomes for women (and men) diagnosed with breast cancer have improved significantly, with now over 80% of women surviving for at least 5 years post-diagnosis. Much of this success has been translated from the bench to the bedside using laboratory models. Here, we outline the types of laboratory models that have helped achieve this and discuss new approaches as we move towards animal-free disease modelling.
| Original language | English |
|---|---|
| Pages (from-to) | 321-327 |
| Number of pages | 7 |
| Journal | Biophysical Journal |
| Volume | 9 |
| Issue number | 4 |
| Early online date | 26 Jul 2017 |
| DOIs | |
| Publication status | Published - Aug 2017 |
| Externally published | Yes |
Bibliographical note
SR receives a studentship from NC3Rs (grant ref.: NC/N00325X/1). VS receives funding from Breast Cancer Now and is involved in running the Breast Cancer Now Tissue Bank.Keywords
- Journal Article
- review
- breast cancer
- ex vivo models
- tissue banks
Access to Document
- Advances in the development of improved animal-free models for use in breast cancer biomedical research
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