Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision

Jan L. Brozek, Jean Bousquet, Carlos E. Baena-Cagnani, Sergio Bonini, G. Walter Canonica, Thomas B. Casale, Roy Gerth van Wijk, Ken Ohta, Torsten Zuberbier, Holger J. Schünemann, David Price

Research output: Contribution to journalArticlepeer-review

1239 Citations (Scopus)


BACKGROUND: Allergic rhinitis represents a global health problem affecting 10% to 20% of the population. The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines have been widely used to treat the approximately 500 million affected patients globally. OBJECTIVE: To develop explicit, unambiguous, and transparent clinical recommendations systematically for treatment of allergic rhinitis on the basis of current best evidence. METHODS: The authors updated ARIA clinical recommendations in collaboration with Global Allergy and Asthma European Network following the approach suggested by the Grading of Recommendations Assessment, Development and Evaluation working group. RESULTS: This article presents recommendations about the prevention of allergic diseases, the use of oral and topical medications, allergen specific immunotherapy, and complementary treatments in patients with allergic rhinitis as well as patients with both allergic rhinitis and asthma. The guideline panel developed evidence profiles for each recommendation and considered health benefits and harms, burden, patient preferences, and resource use, when appropriate, to formulate recommendations for patients, clinicians, and other health care professionals. CONCLUSION: These are the most recent and currently the most systematically and transparently developed recommendations about the treatment of allergic rhinitis in adults and children. Patients, clinicians, and policy makers are encouraged to use these recommendations in their daily practice and to support their decisions.
Original languageEnglish
Pages (from-to)466-476
Number of pages11
JournalJournal of Allergy and Clinical Immunology
Issue number3
Publication statusPublished - Sept 2010


  • adult
  • asthma
  • child
  • child, preschool
  • desensitization, immunologic
  • female
  • guidelines as topic
  • humans
  • infant
  • infant, newborn
  • pregnancy
  • rhinitis, allergic, perennial
  • rhinitis, allergic, seasonal
  • tobacco smoke pollution
  • AR
  • practice guidance


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