An updated systematic review of the impact of medications with anticholinergic activity on cognitive function and mortality

Ian Maidment; Wei-Yee Chan; Nelson Bua; Phyo Myint; Noll Campbell; Malaz Boustani; Chun Shing Kwok; Chris Fox

doi:10.1016/j.jalz.2013.05.1578

An updated systematic review of the impact of medications with anticholinergic activity on cognitive function and mortality

Ian Maidment, Wei-Yee Chan, Nelson Bua, Phyo Myint, Noll Campbell, Malaz Boustani, Chun Shing Kwok, Chris Fox

Research output: Contribution to journal › Abstract › peer-review

Abstract

An estimated 18% of older (≥ 65) adults suffer from mild cognitive impairment (MCI). More than half will progress to dementia within 5 years. Primary prevention may be by recognition of the true burden of anticholinergic drugs on cognition and avoidance wherever possible. This project aimed to systematically review the literature to update a widely used scale that assesses anti-cholinergic burden (ACB scale) and establish the impact of drugs with anticholinergic properties on cognitive function in patients over the age of 18 without a diagnosis of dementia.

Original language	English
Pages (from-to)	P774
Number of pages	1
Journal	Alzheimer's and Dementia
Volume	9
Issue number	4
DOIs	https://doi.org/10.1016/j.jalz.2013.05.1578
Publication status	Published - 2013

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10.1016/j.jalz.2013.05.1578

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title = "An updated systematic review of the impact of medications with anticholinergic activity on cognitive function and mortality",

abstract = "An estimated 18% of older (≥ 65) adults suffer from mild cognitive impairment (MCI). More than half will progress to dementia within 5 years. Primary prevention may be by recognition of the true burden of anticholinergic drugs on cognition and avoidance wherever possible. This project aimed to systematically review the literature to update a widely used scale that assesses anti-cholinergic burden (ACB scale) and establish the impact of drugs with anticholinergic properties on cognitive function in patients over the age of 18 without a diagnosis of dementia.",

author = "Ian Maidment and Wei-Yee Chan and Nelson Bua and Phyo Myint and Noll Campbell and Malaz Boustani and Kwok, {Chun Shing} and Chris Fox",

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AU - Maidment, Ian

AU - Chan, Wei-Yee

AU - Bua, Nelson

AU - Myint, Phyo

AU - Campbell, Noll

AU - Boustani, Malaz

AU - Kwok, Chun Shing

AU - Fox, Chris

PY - 2013

Y1 - 2013

N2 - An estimated 18% of older (≥ 65) adults suffer from mild cognitive impairment (MCI). More than half will progress to dementia within 5 years. Primary prevention may be by recognition of the true burden of anticholinergic drugs on cognition and avoidance wherever possible. This project aimed to systematically review the literature to update a widely used scale that assesses anti-cholinergic burden (ACB scale) and establish the impact of drugs with anticholinergic properties on cognitive function in patients over the age of 18 without a diagnosis of dementia.

AB - An estimated 18% of older (≥ 65) adults suffer from mild cognitive impairment (MCI). More than half will progress to dementia within 5 years. Primary prevention may be by recognition of the true burden of anticholinergic drugs on cognition and avoidance wherever possible. This project aimed to systematically review the literature to update a widely used scale that assesses anti-cholinergic burden (ACB scale) and establish the impact of drugs with anticholinergic properties on cognitive function in patients over the age of 18 without a diagnosis of dementia.

U2 - 10.1016/j.jalz.2013.05.1578

DO - 10.1016/j.jalz.2013.05.1578

M3 - Abstract

SN - 1552-5260

VL - 9

SP - P774

JO - Alzheimer's and Dementia

JF - Alzheimer's and Dementia

IS - 4

ER -

An updated systematic review of the impact of medications with anticholinergic activity on cognitive function and mortality

Abstract

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