Assessment of the efficacy, safety and quality of gentamicin use in Aberdeen Royal Infirmary

K O  Buabeng; A.r. MacKenzie; R B S  Laing; I  Cook; B  Jappy; I M  Gould

Assessment of the efficacy, safety and quality of gentamicin use in Aberdeen Royal Infirmary

K O Buabeng, A.r. MacKenzie, R B S Laing, I Cook, B Jappy, I M Gould

Applied Medicine

Research output: Contribution to journal › Article

7 Citations (Scopus)

Abstract

Fifty-five patients who received od gentamicin were studied. The protocol for od gentamicin was followed in 23/55 (48%). Cure rates were 22/23 (96%) when the protocol was followed and 24/32 (75%) when not followed (P = 0.06). Toxicity was more common in those in whom the protocol was not followed (9/32; 28%) than in those in whom it was followed (1/23; 4%) (P < 0.05). The number needed to treat with the protocol to produce one additional cure was 4.84 (95% CI 2.64 to 28.66) and the number needed to treat to prevent one case of toxicity was 3.61 (95% CI 2.16 to 10.99).

Original language	English
Pages (from-to)	843-845
Number of pages	3
Journal	Journal of Antimicrobial Chemotherapy
Volume	44
Publication status	Published - 1999

Keywords

EDITORIAL RESPONSE
AMINOGLYCOSIDES

Cite this

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title = "Assessment of the efficacy, safety and quality of gentamicin use in Aberdeen Royal Infirmary",

abstract = "Fifty-five patients who received od gentamicin were studied. The protocol for od gentamicin was followed in 23/55 (48%). Cure rates were 22/23 (96%) when the protocol was followed and 24/32 (75%) when not followed (P = 0.06). Toxicity was more common in those in whom the protocol was not followed (9/32; 28%) than in those in whom it was followed (1/23; 4%) (P < 0.05). The number needed to treat with the protocol to produce one additional cure was 4.84 (95% CI 2.64 to 28.66) and the number needed to treat to prevent one case of toxicity was 3.61 (95% CI 2.16 to 10.99).",

keywords = "EDITORIAL RESPONSE, AMINOGLYCOSIDES",

author = "Buabeng, {K O} and A.r. MacKenzie and Laing, {R B S} and I Cook and B Jappy and Gould, {I M}",

year = "1999",

language = "English",

volume = "44",

pages = "843--845",

journal = "Journal of Antimicrobial Chemotherapy",

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publisher = "Oxford University Press",

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T1 - Assessment of the efficacy, safety and quality of gentamicin use in Aberdeen Royal Infirmary

AU - Buabeng, K O

AU - MacKenzie, A.r.

AU - Laing, R B S

AU - Cook, I

AU - Jappy, B

AU - Gould, I M

PY - 1999

Y1 - 1999

N2 - Fifty-five patients who received od gentamicin were studied. The protocol for od gentamicin was followed in 23/55 (48%). Cure rates were 22/23 (96%) when the protocol was followed and 24/32 (75%) when not followed (P = 0.06). Toxicity was more common in those in whom the protocol was not followed (9/32; 28%) than in those in whom it was followed (1/23; 4%) (P < 0.05). The number needed to treat with the protocol to produce one additional cure was 4.84 (95% CI 2.64 to 28.66) and the number needed to treat to prevent one case of toxicity was 3.61 (95% CI 2.16 to 10.99).

AB - Fifty-five patients who received od gentamicin were studied. The protocol for od gentamicin was followed in 23/55 (48%). Cure rates were 22/23 (96%) when the protocol was followed and 24/32 (75%) when not followed (P = 0.06). Toxicity was more common in those in whom the protocol was not followed (9/32; 28%) than in those in whom it was followed (1/23; 4%) (P < 0.05). The number needed to treat with the protocol to produce one additional cure was 4.84 (95% CI 2.64 to 28.66) and the number needed to treat to prevent one case of toxicity was 3.61 (95% CI 2.16 to 10.99).

KW - EDITORIAL RESPONSE

KW - AMINOGLYCOSIDES

M3 - Article

SN - 0305-7453

VL - 44

SP - 843

EP - 845

JO - Journal of Antimicrobial Chemotherapy

JF - Journal of Antimicrobial Chemotherapy

ER -

Assessment of the efficacy, safety and quality of gentamicin use in Aberdeen Royal Infirmary

Abstract

Keywords

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