Biobanking in radiotherapy trials — a challenge to the clinical research community

Duncan C. Gilbert; Valerie Speirs

doi:10.1038/s41571-021-00486-0

Biobanking in radiotherapy trials — a challenge to the clinical research community

Duncan C. Gilbert^* (Corresponding Author), Valerie Speirs^* (Corresponding Author)

^*Corresponding author for this work

University College London

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Precision oncology is predicated on information derived from high-quality tissue samples. Despite almost half of all patients with cancer receiving radiotherapy, samples from these patients are much less commonly available for use in biomarker studies. Biobanks that include material from radiotherapy studies do exist; the challenge is increasing their visibility and accessibility to researchers to continue our efforts to improve outcomes for our patients.

Original language	English
Pages (from-to)	191–192
Number of pages	3
Journal	Nature Reviews Clinical Oncology
Volume	18
Early online date	17 Feb 2021
DOIs	https://doi.org/10.1038/s41571-021-00486-0
Publication status	Published - 1 Apr 2021

Bibliographical note

Acknowledgements
The authors wish to thank N. Curtin for initiating and contributing to this work, T. Ward (patient representative) and G. Higginbotham for their input, and the National Cancer Research Institute (NCRI) Clinical and Translational Radiotherapy Research Working Group (CTRad) and Cellular Molecular Pathology Initiative (CMPath) for making this work possible.

Keywords

Oncology
radiotherapy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

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abstract = "Precision oncology is predicated on information derived from high-quality tissue samples. Despite almost half of all patients with cancer receiving radiotherapy, samples from these patients are much less commonly available for use in biomarker studies. Biobanks that include material from radiotherapy studies do exist; the challenge is increasing their visibility and accessibility to researchers to continue our efforts to improve outcomes for our patients.",

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author = "Gilbert, {Duncan C.} and Valerie Speirs",

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AU - Speirs, Valerie

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N2 - Precision oncology is predicated on information derived from high-quality tissue samples. Despite almost half of all patients with cancer receiving radiotherapy, samples from these patients are much less commonly available for use in biomarker studies. Biobanks that include material from radiotherapy studies do exist; the challenge is increasing their visibility and accessibility to researchers to continue our efforts to improve outcomes for our patients.

AB - Precision oncology is predicated on information derived from high-quality tissue samples. Despite almost half of all patients with cancer receiving radiotherapy, samples from these patients are much less commonly available for use in biomarker studies. Biobanks that include material from radiotherapy studies do exist; the challenge is increasing their visibility and accessibility to researchers to continue our efforts to improve outcomes for our patients.

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ER -

Biobanking in radiotherapy trials — a challenge to the clinical research community

Abstract

Bibliographical note

Keywords

UN SDGs

Access to Document

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